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Glyceryl Triacetate Market:

China produces lots of Glyceryl triacetate (Triacetin). In 2010, the output of glyceryl triacetate in China was 55,000 tons. The output of other countries in 2010, such as US and UK were 15,000 tons. Other countries’ output, like Japan, were about 8,000 tons. There are about 20 glyceryl triacetate producers in China, and Ruijia Chemical is the largest triacetin producer. Yixing is were most of the triacetin is produced. Glyceryl triacetate is used in different industry. For instances, tobacco industry, casting industry, food, spice, pharmaceutical industries, and inks, dyes, plastics processing industries.

Glyceryk Triacetate Used in Research Glyceryl triacetate is used to treat in Canavan disease but it’s still testing. “Canavan disease (CD) is a fatal dysmyelinating genetic disorder associated with aspartoacylase deficiency, resulting in decreased brain acetate levels and reduced myelin lipid synthesis in the developing brain.” Scientists tested tolerability of glyceryl triacetate at low dose in two infants with CD for 4.5 and 6 months. And higher dose of glyceryl triacetate was used on rat. At the end of the low dose trial with infants and high dose trial with rat, “GTA treatment caused no detectable toxicity and the patients showed no deterioration in clinical status.”

“Triacetin, also known as Glyceryl Triacetate, is reported to function as a cosmetic biocide, plasticizer, and solvent in cosmetic formulations, at concentrations ranging from 0.8% to 4.0%.” It is was recognized as safe human food ingredient by FDA. Triacetin was found not toxic to animal and human in acute oral or dermal exposures. However, on study showed that triacetin could cause erythema, slight edema, alopecia, and desquamation, and irritation in rabbits’ eyes. “In humans, triacetin reportedly has caused ocular irritation but no injury.”