User:Bushra.alkayan/sandbox

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RenehaVis
''' Renehavis is a sterile viscoelastic device whose active ingredient is a natural derivative of hyaluronic acid obtained by biofermentation An innovative product for knee OA, RenehaVis™ is the only product in the world that contains 2 Hyaluronic Acids in 1 syringe for a sequential injection. RenehaVis offers to both patients and doctors the DMC concept: Dual Molecular weight and Concentration concept in 1 syringe. Low molecular weight HA has 2 other functions: •Diffuse through the cartilage to protect the chondrocytes (note: a molecule which help create endogenous HA and proteoglycans) which are commonly destroyed in knee OA patients. This is often terms as the CAGING EFFECT. •Diffuse to the synoviocytes at the synovial membrane to activate them. This results in the generation of endogenous HA. This action is known as the MECHANOSENSITIVE EFFECT.
 * Not chemical ( cross linked )
 * Not contain any protein of avian origin
 * Chamber 1 contains: Low molecular weight HA – High concentration
 * Chamber 2 contains: High molecular weight HA – Low concentration
 * The high molecular weight HA is at a lower concentration as it only has 1 function (shock absorber) and it only has to maintain this function whilst the low molecular weight HA acts.

0.7 ml of LMW (1 MD) contain 22 mg/ml

07 ml of HMW (2 MD) contain 10 mg/ml