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Angiocentric gliomas are low-grade gliomas predominantly seen in children and young adults. Angiocentric glioma was first recognized as a distinct Grade I tumor in the 2007 World Health Organization Classification of Tumors of the Central Nervous System. It is most commonly associated with seizures, with 95% of patients presenting with intractable seizures.

Pathology
Angiocentric glioma has historically been confused to Cortical ependymoma due to the presence of radially oriented cell processes in the direction of vessels, forming pseudorosettes and presence of piloid cells.