User:CellbioMAA/Sandbox

Micronuclei

=History=

Theodor Boveri originally observed the fact that abnormal nuclear morphologies commonly occurred in cancer. Micronuclei are also referred to Howell-Jolly bodies; founded by hematologists William Henry Howell and Justin Marie Jolly in erythrocytes. Micronuclei induction by a chemical was first reported in Ehrlich ascites tumor cells treated with colchicine. The affect of environmental stressors on the expression of micronuclei was first analyzed in root tip cells under ionizing radiation. It can be inferred that nuclear abnormalities are a result of various molecular mechanisms. These events can ultimately lead to cell death.

=Description=

Formation
=Role in Cancer=

Micronuclei are often overlooked in cancer

=Identification=

Detection Tests
Micronucleus test

Usefulness
=References=