User:Cgarcia9530/C1QTNF5

C1q and tumor necrosis factor related protein 5, also known as C1QTNF5, is a protein which in humans is encoded by the C1QTNF5 gene, associated with late-onset retinal degeneration( otherwise known as L-ORD). The C1QTNF5 gene secreted and membrane-linked to a protein which is strongly expressed in retinal pigment epithelium cells.

'''C1QTNF5 gene is associated with late-onset retinal degeneration otherwise known as L-ORD. Retinal degeneration is a genetic disorder that originates from the retina, a thin layer located towards the back part of the eye that senses for light. C1QTNF5 gene associated with L-ORD leads to poor eye sight in dim to dark light which evetually evolves into night blindness known as nyctalopia .'''

C1QTNF5 gene is caused by a mutation in the S163R, found in the gobular c1q domain '''. C1q domain binds to lignads thrughout the body that help boost immune responses. The C1q protein determines the different types of potential bacteria and viruses lignands.  When there is a mutation in the C1q protein the gobular subunits within the C1q that contain binding cites for immune lignands become halted causing L-ORD and retinal pigment epithelium.'''