User:Chandler.c.ho/sandbox

PubMed Assignment
Hemoglobin is composed of two alpha globin and two beta globin chains. Deletions in alpha globin gene or point mutations in beta globin gene can contribute thalassemia. Seven common deletions in alpha thalassemia can be detected in a multiplex polymerase chain reaction.

Unlike alpha thalassemia, beta thalassemia is predominantly caused by point mutations.

/Terminator (genetics)
Prokaryotes

1. transcription arrest by Rna pol and endonuclease Uvr(A) triggered by damage dna

2. rho dependent terminator description of rut site atp dependent 3 purposed mechanism rho act on polymerase by pushing rho act on rna by pulling rho induces a conformational change in polymerase

3.rho-independent terminator requires no other factor show sequence element

Eurkaryotes

1.Torpedo model

2.alloseteric model

to be continue