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Ketosteril is used in prevention and therapy of damages due to faulty or deficient portein metabolism in chronic renal insufficiency in connection with limited protein in food to 40 grams per day (for adults) and less; i.e. generally in patients with a glomerular filtration rate (GFR) below 25 ml/min.

primary use
with low protein diet， prevent and treat Protein metabolism disorder caused by chronic kidney disease. indication: GFR lower than 25ml/min. adult need low protein diet within 40g protein intake per day

dosage: oral: 3 times/day, 4-8 tablets everytime, intake before meals. (this for weight=70Kg). * please follow your doctors prescription

effect:
most of chronic renal failure patients' protein and amino acid metabolism disorder, in negative nitrogen balance condition. Ketoacid can supplement amino acid and reduce the urea, alleviate uremia condition, improve nutrition.

low protein diet + ketoacid can achieve follow effect:

1, alleviate uremia condition.

2,protect remain kidney function, prolong kidney disease progress

3,keep patients' nutrition supplement

4,reduce the complications caused by chronic renal failure

clinic observation show that low protein diet + ketoacid can alleviate below complications:

1, alleviate uremia condition.

2, prevent body protein degradation

3, alleviate proteinuria

4, improve calcium phosphorus metabolism disorders, secondary hyperparathyroidism and renal osteodystrophy

5, improve carbohydrate metabolism to balance

6, Improved lipid metabolic disorder

7. improve endocrine disorders

DRUG INTERACTIONS
may cause hypercalcemia

Drug Interactions
The simultaneous administration of medicaments containing calcium (e.g. acetolyte) may lead to pathological increases of the serum calcium level or intensification thereof.

As the uremic symptoms improve under Ketosteril, a possible administration of aluminum hydroxide should be reduced. Pay attention to a reduction of serum phosphate.

In order not to interfere with absorption, do not take drugs together with Ketosteril that form sparingly soluble compounds with calcium (e.g. tetracyclines, chinolone like ciprofloxacin and norfloxacin, iron-, fluoride- and estramustin-containing drugs). Between the intake of Ketosteril tablets and drugs from the mentioned categories a period of at least 2 hours should pass.

If the blood calcium concentration raises by the intake of Ketosteril, the susceptibility towards certain drugs enhancing the heart strength (heart/cardiac-active glycosides) will increase and the risk of heart rhythm disturbance will increase.