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Syphilishttps://en.wikipedia.org/wiki/History_of_syphilis

This common theory[4] holds that syphilis was a New World disease brought back by Columbus, Martín Alonso Pinzón, and/or other members of their crews as an unintentional part of the Columbian Exchange.

Citation:Tampa, M., et al. “Brief History of Syphilis.” Journal of Medicine and Life, vol. 7, no. 1, Carol Daila University Foundation, 2014, pp. 4–10.

Quote:The Columbian hypothesis. This very popular hypothesis states that the navigators in Columbus fleet would have brought the affliction on their return form the New World in 1493

DOI: 10.1016/j.jaad.2005.10.003

Tampa, M., et al. “Brief History of Syphilis.” Journal of Medicine and Life, vol. 7, no. 1, Carol Daila University Foundation, 2014, pp. 4–10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956094/ This article goes a little more into detail about the medical treatment used for syphilis. It will cover how there wasn't a known treatment for syphilis when it first arrived. It will also give a brief description of how it arrived to Europe.

Cody Copeland

Mrs. Coffman

Early United States History 2010

10/15/21

The History of Syphilis

Syphilishttps://en.wikipedia.org/wiki/History_of_syphilis

This common theory[4] holds that syphilis was a New World disease brought back by Columbus, Martín Alonso Pinzón, and/or other members of their crews as an unintentional part of the Columbian Exchange.

Citation:Tampa, M., et al. “Brief History of Syphilis.” Journal of Medicine and Life, vol. 7, no. 1, Carol Daila University Foundation, 2014, pp. 4–10.

Quote:The Columbian hypothesis. This very popular hypothesis states that the navigators in Columbus fleet would have brought the affliction on their return form the New World in 1493

DOI: 10.1016/j.jaad.2005.10.003

Tampa, M., et al. “Brief History of Syphilis.” Journal of Medicine and Life, vol. 7, no. 1, Carol Daila University Foundation, 2014, pp. 4–10.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956094/

This article goes a little more into detail about the medical treatment used for syphilis. It will cover how there wasn't a known treatment for syphilis when it first arrived. It will also give a brief description of how it arrived to Europe.

Hook, Edward W, Prof. “Syphilis.” The Lancet (British Edition), vol. 389, no. 10078, Elsevier Ltd, 2017, pp. 1550–57, doi:10.1016/S0140-6736(16)32411-4.

'http://www.oxfordartonline.com/

This article covers the effects of syphilis on people in Europe. It talks about how important a cure was.It will go into detail about works that have been found depicting people looking for cures.

Fact 1 Paragraph: Paracelus (1493-1541) was one of the first supporters of the mercury treatment. Mercury was used in Arabic medicine in the treatment of several dermatomes as well as leprosy, and succeeded to gain rapidly an important place in medical field at that time. Mercury is a potent diuretic that also leads to excessive salivation when administered in toxic doses. At the time, is was considered that the “virus” was eliminated from the body through sweat, salivation and diuresis [15,33,34]. There were several methods of administering mercury. Thus, in a mixture with grease, mercury was administered topically, leading to ulcerations. Barbarossa pill, named after the Turk admiral who gave the pill to his soldiers and was affected by the malady, contained a mixture of mercury and perfume essence and fruit flavours [7]. Mercurous chloride (calomel, Hg2Cl2) was a white salt able to be administered orally, topically or by injections. The metallic form of mercury was administered also under the form of therapeutic fumigation. Patients seemed to find the adverse reactions of the treatment acceptable, however, the treatment lead to systemic intoxication (hidrargirism) and pneumonia [33].

Fact 1 Summary: One of mercury's many ways of being applied was by topical solutions.

Fact 2 Paragraph: The natural history of syphilis is one of a chronic infection that can cause a series of highly variable clinical manifestations during the first 2–3 years of infection, followed by a typically prolonged latent stage that can evolve into clinically apparent tertiary infection stage years or even decades after initial infection.6, 20 Because syphilis lesions are often asymptomatic and can occur in regions of the body where they might go unnoticed, not all infected people have classic signs of one or more of the clinical stages of infection. The disease is sexually infectious to others only when the early, primary and secondary stages are present; however, congenital transmission can occur years after entering latency.

Fact 2 Summary: Syphilis was known to go unnoticed back in the day.

Giorgio Sommariva of Verona is recorded to have used mercury to treat syphilis in 1496, and is often recognized as the first physician to have done so, although he may not have been a physician. One of mercury's many ways of being applied was by topical solutions. DOI: 10.1016/j.jaad.2005.10.003

The first well-recorded European outbreak of what is now known as syphilis occurred in 1495 among French troops besieging Naples, Italy.[1][21] It may have been transmitted to the French via Spanish mercenaries serving King Charles of France in that siege. Syphilis was known to go unnoticed back in the day. doi:10.1016/S0140-6736(16)32411-4.