User:Ctp8678/sandbox

Is everything in the article relevant to the article topic? Is there anything that distracted you?


 * Yes, everything was very relevant to the topic. The discussion about immunosuppression was distracting because it was more applicable to tumor development than to cutaneous changes

Is the article neutral? Are there any claims, or frames, that appear heavily biased toward a particular position?


 * The article is neutral; there does not appear to be any heavily biased claims

Are there viewpoints that are overrepresented, or underrepresented?


 * No apparent overrepresentation or underrepresentation

Check a few citations. Do the links work? Does the source support the claims in the article?


 * Yes, links work

Is each fact referenced with an appropriate, reliable reference? Where does the information come from? Are these neutral sources? If biased, is that bias noted?


 * Most facts are referenced with appropriate sources. Information comes from book chapter, websites, journals.  Some of these sources are not neutral because they also sell products, which may cause a financial conflict of interest

Is any information out of date? Is anything missing that could be added?


 * Information is generally up to date. However, there is information missing in regards to how skin moisture factors into photoaging.  There could be a lot more information discussed in regards to treatment and prevention options, ie the different types of retinoid options.  There have also been new technology in tertiary prevention methods

Check out the Talk page of the article. What kinds of conversations, if any, are going on behind the scenes about how to represent this topic?


 * There are no conversations going on. The last comment was made 9 years ago.

How does the way Wikipedia discuss this topic differ from the way you would talk about it grand rounds?


 * Grand rounds is usually presented as an interesting case, not strictly informative

I intend on expanding on the lead as well as treatment and prevention options for photoaging. I will also discuss how moisture and transepidermal water loss play a role in intrinsic changes that occur with aging. Suggested Edits for Photoaging

Skykryswest (talk) 11:36, 10 April 2018 (UTC)Each of these treatment modalities have primary concerns that they address. For example, botulinum injections paralyze facial muscles. This prevents muscle contraction and subsequent wrinkle formation. Injectable fillers are often used in the nasolabial fold to increase volume and minimize the appearance of sagging or wrinkling.
 * Appropriate images might add value to the article
 * Expansion of the Treatment (including preventive measures) section could be beneficial, especially with respect to more current and updated options.
 * The most recent source cited in this article is from 2008 - could definitely use some updating.
 * Very interesting - good luck girl!

Sun protection is the most effective form of primary prevention of photoaging. The major methods of sun protection are sunscreen products, sun protective clothing, and reducing exposure to the sun, especially during peak sun hours (10 AM-4PM in the spring and summer seasons). Broad-spectrum sunscreen products provide optimal coverage for protection against UV damage because they protect against both types of UVA rays (UVA1 and UVA2) along with UVB rays. Proper application methods and timing are important factors in proper sunscreen use. This includes using a proper quantity of sunscreen, applying sunscreen prior to sun exposure, and consistent reapplication (especially after exposure to water or sweat).

There are various treatment modalities for secondary prevention. Tretinoin, a retinoid, is widely considered to be the most efficacious treatment for photoaging by dermatologists due to consistent evidence from several randomized clinical trials. Retinoids are vitamin A derivatives that bind to retinoic acid receptors and retinoid X receptors. Binding to these receptors induces a cascade of cellular processes that ultimately lead to increased collagen production and epidermal thickening, reducing the appearance of skin sagging and wrinkling.

There are various forms of topical retinoids. Tretinoin is the most widely accepted and studied retinoid for photoaging. Tretinoin is also efficacious for the treatment of acne. Adapalene and tazarotene are also third-generation synthetic retinoids that are used for the treatment for acne. Adapalene has not been widely studied or proven for use in photoaging. However, it has been used off-label for that purpose. Tazarotene is been proven to be efficiacious in the treatment of photoaging. Retinoid derivatives, known as retinol and retinal, are often used in over the counter cosmeceutical products for anti-aging purposes. The form of retinol and retinal are metabolized in the skin to retinoic acid, which can then act on the RARs and RXRs. These products are considered cosmeceuticals rather than drugs due to their lack of regulation, and they have not been widely studied. Furthermore, tretinoin is the most well studied and consistent in its efficacy in the treatment of photoaging.

There are various forms of tertiary prevention of photoaging.