User:DNADude

Protein Translation Engineering. The process of manipulating DNA code and conditions which affect the interaction of mRNA at the ribosome level to link amino acids together to form proteins. This process can include, but is not limited to silent changes or changes which substitute or delete amino acids from the final protein. In addition to direct manipulation of DNA code, translation engineering can be controlled and effected by changing the environment in which the the DNA message interacts with the ribosome. This can include but is not limited to, temperature, the abundance (or lack thereof) of key tRNAs, induction times and a variety of other factors including choice of cell line for protein express.

Silent changes and translation engineering DNA interacts with the ribosome, three letters at a time. These three letters or triplets are called "codons". All of the millions proteins in every living thing are composed of amino acids, the essential building blocks of life. For each amino acid, multiple codons exist, each