User:Dag330/sandbox

Antioxidant Hypothesis
I believe an issue with the antioxidant article is that it does not mention the Antioxidant Hypothesis - the source of all the confusion. It is not explained why that it was a strongly pursued theory that antioxidants would be have huge benefits.

Proof that the Antioxidant Hypothesis exists:


 * Reconvene and reconnect the antioxidant hypothesis in human health and disease https://www.ncbi.nlm.nih.gov/pubmed/21731194
 * The antioxidant hypothesis is dead. How many Danes died with it? https://www.ncbi.nlm.nih.gov/pubmed/16942695
 * On the antioxidant hypothesis with regard to arteriosclerosis https://www.ncbi.nlm.nih.gov/pubmed/3510621
 * Optimum plasma levels of antioxidant micronutrients. Ten years of antioxidant hypothesis on arteriosclerosis https://www.ncbi.nlm.nih.gov/pubmed/7695592
 * The antioxidant hypothesis of cardiovascular disease: epidemiology and mechanisms. https://www.ncbi.nlm.nih.gov/pubmed/2088799
 * MedRS:
 * Not MedRS but evidence of the term:

"Although scientific rationale and observational studies have been convincing, randomised primary and secondary intervention trials have failed to show any consistent benefit from the use of antioxidant supplements on cardiovascular disease or cancer risk, with some trials even suggesting possible harm in certain subgroups. These trials have usually involved the administration of single antioxidant nutrients given at relatively high doses. The results of trials investigating the effect of a balanced combination of antioxidants at levels achievable by diet are awaited."

Antioxidant Exercise Research
For Antioxidant Exercise:

Rewrite of Lead
I think the lead needs some rewriting.

Proposed Sentence 1
An antioxidant is a class of organic compounds that inhibit the oxidation of other molecules. Changes were made with David's help.

Proposed Sentence 2
Antioxidant compounds are found in most forms of aerobic life, including plants and animals. Antioxidants include essential organic molecules found in the tissues of plants and animals. They are also synthesized for use in industrial applications as fuel additives and polymer stabilizers.

They have a critical role in cell biology. They are also synthesized for use in industrial applications as fuel additives and polymer stabilizers.

In the body, antioxidants...

In industry, antioxidants...

As oxidation has the potential to degrade many substances, antioxidants are used to stabilize fuels; lubricants; and polymers such as rubber, plastics, and adhesives.

The term "antioxidant" is mainly used for two different groups of substances: industrial chemicals which are added to products to prevent oxidation, and natural chemicals found in foods and body tissue which are said to have beneficial health effects.

In cell biology, oxidation can produce free radicals, leading to chain reactions that may damage cells. Antioxidants such as thiols or ascorbic acid (vitamin C) can stop these chain reactions.

(are there any inorganic antioxidants?)

Antioxidants have an important role in cell biology.

Other Issues

 * The history section may need to be expanded. Consider breaking up into subsections on evolution of biological antioxidants and the history of their discovery in the 19th century. Expand on early uses.
 * Can we include a list of antioxidants? (we already link to the article)