User:Damid001/sandbox

[edit on Wikidata] In neuroscience, stellate cells are any neuron that have a star-like shape formed by dendritic processes radiating from the cell body.

Most stellate neurons are the inhibitory interneurons found within the upper half of the molecular layer (ML) of the cerebellum. Cerebellar stellate cells synapse onto the dendritic arbors of Purkinje cells, and, like basket cells, send inhibitory signals from the ML to the Purkinje Cell Layer (PCL).[1] Cortical spiny stellate cells are found in layer IVC of the V1 region in the visual cortex.[2] They receive excitatory synaptic fibres from the thalamus and process feed forward excitation to 2/3 layer of V1 visual cortex to pyramidal cells. Cortical spiny stellate cells have a 'regular' firing pattern. Stellate cells are chromophobes, that is cells that does not stain readily, and thus appears relatively pale under the microscope.

-Basket cells -> migration

-ML (molecular layer?)

In the somatosensory barrel cortex of mice and rats, glutamatergic spiny stellate cells are organized in in barrels of layer 4

Contents:

1. Structure

2. Development

--Migration from the ML of the cerebullum: Stellate and basket cells originate from the cerebellar ventricular zone (CVZ) along with Purkinje cells and Bergmann glia

"various layers" = Internal granular layer (IGL) and Purkinje cell layer (PCL)

All->most Stellate cells are GABAergic and inhibitory.

--Relationship between Stellate and other neurons (Basket, Purkinje)

Stellate cells are produced after Purkinje cells and before granule cells.

3. Clinical Significance

--Pancoast syndrome?