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Education
Cox attended Stanford University where she earned her Bachelor of Arts degree in 1911. She earned her Masters of Arts degree in German language and literature in 1913. Following graduation, she moved to Berlin, Germany where she spent her time at the University of Jena and the University of Berlin. While in Germany, she joined the American Friends Service Committee in its relief efforts to provide food to starving children who were affected by World War I. Her partnership with the American Friends Service Committee was likely inspired by her background as a Quaker, also known as the Society of Friends.

Catharine and Walter
After a year long employment with the Central Mental Hygiene Clinic at Cincinnati General Hospital, the Children's Hospital, and the Diagnostic Center of the Veterans Bureau, Cox returned to Stanford to work with Dr. Terman in 1927. Cox soon met one of Dr. Terman's colleagues, Walter Miles, and the two were married the same year. Walter, a widower, had three teenaged children: Thomas, Caretta, and Kirk, all of whom Catharine raised as her own. Catharine and Walter also had two children of their own; a girl, Anna Mary Miles (Jones) and a son, Charles Elwood, who died at birth.