User:Dhinesh Muthusamy fury/sandbox

Glutathione deficiency is the decreased synthesis of glutathione from the body. for eg; glutathione is synthesised in the lens which needs NADPH. NADPH got used up in the production of sorbitol in sorbitol pathway of glucose metabolism which happens during hyperglycaemic condition. thus glutathione being a antioxidant, whose deficiency may lead to increased accumulation of oxidative species and cause damage to cells and with the above example it causes cataract in diabetic.