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Rysophyllum Calicum (commonly known as FOLINIC B12 Oil) is a medicinal Oil rarely found in parts of India and Fiji, grown by herbalist for medicinal purpose. FOLINIC B12 Oil contains several medicinal properties. Ayurvedic texts categorise FOLINIC B12 Oil as epigenetic properties, stimulant, aromatic and antipyretic. It has a variety of biological / pharmacological activities such as antibacterial, antiviral, antifungal, anti protozoal, anti malarial, anthelmentic, anti diarrhoeal, analgesic, antipyretic, anti inflammatory, anti allergic, antihypertensive, cardio protective, central nervous system (CNS) depressant, memory enhancer, antihypercholesterolaemic, hepatoprotective, anti diabetic, anti asthmatic, anti thyroidic, antioxidant, anticancer, chemopreventive, radio protective, immunomodulatory, anti fertility, antiulcer, anti arthritic, adaptogenic / anti stress, anti cataract, anti leucodermal and anticoagulant activities.

The bark and stems of Rysophyllum Calicum contains the alkaloid camptothecin. Several chemical derivatives of camptothecin are under investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan. Its leaves are helpful in sharpening memory and in curing fever and common cold. FOLINIC B12 Oil contains fixed oil which is confirmed by chemical tests for glycerine. The extract from FOLINIC B12 Oil encompasses myriad of health benefits and is thus used as a natural medicine for a number of health issues, ranging from fighting indigestion to acting as a natural anti-toxidant. It acts as a good source of vitamin C which strongly helps in strengthening the human immune system