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Introduction
Takayasu arteritis commonly occurs in woman younger than age 50 years; however, it has been reported in patients as young as age 6 months (see Pediatric Takayasu Arteritis). Takayasu arteritis can manifest as isolated, atypical, and/or catastrophic disease. It can involve any or all of the major organ systems. The disease has been reported in all parts of the world, although it appears to be more prevalent in Asians.

Signs and symptoms
Approximately 10% of patients with Takayasu arteritis are asymptomatic. Clinical manifestations are heterogeneous and include the following:


 * Systemic (eg, malaise, arthralgias, fever) - May precede clinical vascular involvement
 * Cardiac and vascular (eg, bruit, especially carotid; blood pressure difference of extremities, claudication, hypertension)
 * Neurologic (eg, headache, visual disturbance)
 * Dermatologic (eg, erythema nodosum)

Diagnosis
The American College of Rheumatology classification for Takayasu arteritis requires the presence of 3 of the following 6 criteria:


 * Age of 40 years or younger at disease onset
 * Claudication of the extremities
 * Decreased pulsation of one or both brachial arteries
 * Difference of at least 10 mm Hg in systolic blood pressure between arms
 * Bruit over one or both subclavian arteries or the abdominal aorta
 * Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the upper or lower extremities that is not due to arteriosclerosis, fibromuscular dysplasia, or other causes

Takayasu arteritis can be divided into the following six types based on angiographic involvement :


 * Type I - Branches of the aortic arch
 * Type IIa - Ascending aorta, aortic arch, and its branches
 * Type IIb - Type IIa region plus thoracic descending aorta
 * Type III - Thoracic descending aorta, abdominal aorta, renal arteries, or a combination
 * Type IV - Abdominal aorta, renal arteries, or both
 * Type V - Entire aorta and its branches

A young lady with severe Type 1 and 5
A young lady had history of severe neck swelling, intermittent claudication, low grade fever and myalgia for more than 3 years and treated symptomatically by their physician and other specialists. Her complaints were not relieved. Finally she came for reevaluation and treatment and she was diagnosed with Takayasu Arteritis with the involvement of left common carotid artery ostial sub total occlusion and bilateral iliac artery severe narrowing, approximately 90% long segment stenosis.

Dr AM Thirugnanam, First Retrograde Carotid Angioplasty
Under general anesthesia, left external carotid artery was surgically opened and connected with one plastic tube and its other end with one 7 Fr sheath. The lesion from distal to proximal was dilated with 5 mm non compliant balloon and deployed three stents in the left common carotid to bifurcation