User:Drew.Broda/Flap (surgery)

Anatomy
"Plastic surgery is a constant battle between blood supply and beauty." - Sir Harold Gilles Jr.

Anatomy of a Flap
Flaps can contain many different combination of layers of tissue, from skin to bone (see classification section). The main goal of a flap is to maintain blood flow to tissue to maintain survival and understanding the anatomy in flap design is key to a successful flap and surgery.

Skin Anatomy
Flaps may include skin in their construction. Skin is important for many reasons, but namely its role in thermoregulation, immune function, and blood supply aid in flap survival. The skin can be divided into three main layers including the epidermis, the dermis, and the subcutaneous tissue. Blood is supplied to the skin mainly by two networks of blood vessels. The deep network lies between the dermis and the subcutaneous tissue, while the shallow network lies within the papillary layer of the dermis. The epidermis is supplied by diffusion from this shallow network and both networks are supplied by collaterals, and by perforating arteries that bring blood from deeper layers either between muscles (septocutaneous perforators) or through muscles (musculocutaneous perforators).

This robust and redundant blood supply is important in flap surgery. This is important because flaps rely on named blood vessels and redundancy in blood supply since the flap will be cut off from other blood vessels when the flap is raised and removed from its surrounding native tissue. The remaining blood supply must then keep the tissue alive until a additional blood supply can be formed through a process called angiogenesis.

The Angiosome
The angiosome is a concept first coined by Ian Taylor in 1987. The angiosome is a three-dimensional region of tissue that is supplied by a single artery and can include skin, soft tissue, and bone. Adjacent angiosomes are connected by narrower choke vessels and so multiple angiosomes can be supplied by a single artery. The angiosome can be further broken down into the arterial supply, the arteriosome, and the venous supply, the venosome. Knowledge of these supply arteries and their associated angiosomes is useful in planning the location, size, and shape of a flap.

Uses
Flap surgery is a technique essential to plastic and reconstructive Surgery. A flap is defined as a tissue that can be moved to another site and has its own blood supply. This is in comparison to a skin graft which does not have its own supply blood supply and relies on vascularization from the recipient site. Flaps have many uses in wound healing and are used when wounds are large, complex, or need tissue and bulk for successful closure.

Common uses:


 * Abdominal wall reconstruction
 * Breast reconstruction
 * Hand reconstruction
 * Mandible reconstruction
 * Rhinoplasty
 * Scar revision
 * Skin cancer

Contraindications
Anyone who is unstable for surgery should not undergo flap surgery. While not absolute contraindications for flap surgery, there are a few contraindications to know. As with most surgeries, people who are sicker may have more difficulties with wound healing. This includes people with comorbidities such as diabetes, smoking, immunosuppression, and vascular disease.

Risks/Complications
The risks of flap surgery include infection and wound breakdown, fluid accumulation, bleeding, damage to nearby structures, and scarring. The most notable risk in this procedure is flap death, where the flap loses blood supply. The loss of blood can be due to many reasons, but is commonly due to tension on the vascular supply and not enough blood flow to the end segments of the flap. This can sometimes be fixed with another surgery or using additional methods of healing in the reconstructive ladder.

Anatomy
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Classification
Further information: List of plastic surgery flaps

Flaps can be fundamentally classified by their mechanism of movement, the types of tissues present, or by their blood supply. The surgeon should choose the least complex type that will achieve the desired effect, a concept known as the reconstructive ladder.

Mechanism of Movement
Flaps can be classified according to level of complexity.

Local flaps
Local flaps are created by freeing a layer of tissue and then stretching the freed layer to fill a defect. This is the least complex type of flap and includes advancement flaps, rotation flaps, and transposition flaps, in order from least to most complex. With an advancement flap, incisions are extended out parallel from the wound, creating a rectangle with one edge remaining intact. This rectangle is freed from the deeper tissues and then stretched (or advanced) forward to cover the wound. The flap is disconnected from the body except for the uncut edge which contains the blood supply which feeds in horizontally. A rotation flap is similar except instead of being stretched in a straight line, the flap is stretched in an arc. The more complex transposition flap involves rotating an adjacent piece of tissue, resulting in the creation of a new defect that must then be closed.

Regional flaps
Regional or interpolation flaps are not immediately adjacent to the defect. Instead, the freed tissue "island" is moved over or underneath normal tissue to reach the defect to be filled, with the blood supply still connected to the donor site via a pedicle. This pedicle can be removed later on after new blood supply has formed, e.g., PMMC, DP flaps for head and neck defects, TRAM for breast reconstruction.

Distant flaps
Distant flaps are used when the donor site is far from the defect. These are the most complex class of flap. Direct or tubed flaps involve having the flap connected to both the donor and recipient sites simultaneously, forming a bridge. This allows blood to be supplied by the donor site while a new blood supply from the recipient site is formed. Once this happens, the "bridge" can be disconnected from the donor site if necessary, completing the transfer. A free flap has the blood supply cut and then reattached microsurgically to a new blood supply at the recipient site.

Tissue type
Flaps can be classified by the content of the tissue within them.

Cutaneous
Contain the full thickness of the skin, fat, and superficial fascia and are used to fill small defects. These are typically supplied by a random blood supply. Examples: Z-plasty, deep inferior epigastric perforator (DIEP) flap, V-Y advancement flap.

Fasciocutaneous
Contain subcutaneous tissue and deep fascia, resulting in a more robust blood supply and ability to fill a larger defect. Cormack and Lamberty classification is used for vascular supply of faciocutaneous flaps. Examples: temporoparietal and anterolateral thigh fascocutaneous flap, lateral fasciocutaneous flap, posterior fasciocutaneous flap.

Musculocutaneous and Muscle flaps
Contain a layer of muscle to provide bulk that can fill a deeper defect. If skin cover is needed, a skin graft can be placed over top of it. Examples: gastrocnemius flap, latissimus flap, transverse rectus abdominis myocutaneous (TRAM) flap, transverse upper gracillis (TUG) flap.

Bone
Contain bone and are used when structural support is needed such as in jaw reconstruction. Example: fibula flap.

Omental and Intestinal
Omental flaps can be used in chest wall defects and intestinal flaps can be used to reconstruct tubular structures like the esophagus.

Vascular
Classification based on blood supply to the flap:

Axial

 * Axial flaps are supplied by a named artery and vein. This allows for a larger area to be freed from surrounding and underlying tissue, leaving only a small pedicle containing the vessels.
 * Reverse-flow flaps are a type of axial flap in which the supply artery is cut on one end and blood is supplied by backwards flow from the other direction.

Random
Random flaps are simpler and have no named blood supply. Rather, they are supplied by generic vascular networks and follow a 3:1 length to width ratio.


 * Pedicled flaps remain attached to the donor site via a pedicle that contains the blood supply, in contrast to a free flap as described under Classification by complexity.
 * Pedicled flaps remain attached to the donor site via a pedicle that contains the blood supply, in contrast to a free flap as described under Classification by complexity.

Recovery or Rehabilitation
Healing after flap surgery is complex and length of time for healing is variable depending on the type of flap. The main goal is to maintain adequate blood flow to the flap during the stages of wound healing.

History
Skin flaps are an essential part of a surgeon’s toolbox in Plastic Surgery. It is part of the Reconstructive Ladder, a stepwise approach to wound closure.

The first known reports of surgical flaps originated in 600 BCE in India by Sushruta where the Tilemakers caste would reconstruct noses using regional flaps due to the practice of nose amputations as a form of legal punishment. The next description of flap surgery comes from Celsus an ancient Roman who described advancement skin flaps from 25 BC to 50 AD. In the 15th century, Gaspare Tagliacozzi an Italian surgeon helped develop the “Italian Method” for nasal reconstruction, a delayed pedicle skin graft, where the skin from the arm would be attached to the nose for many months to create the reconstruction, first printed in the 1597 book De Curtorum Chirurgia per Insitionem. The Italian method was rediscovered in 1800 by German surgeon Carl Ferdinand von Graefe. Major advancements in modern Plastic Surgery are mostly attributed to Harold Gilles who pioneered facial reconstruction during World War I using pedicled tube flaps on patients such as Walter Yeo and the development of the walking-stalk skin flap by Gilles' cousin Archibald McIndoe in 1930.

Advancements continued in flap surgery. With the introduction of the Operating Microscope Microvascular surgery advancements allowed for the anastomosis of blood vessels. This led to the ability of free tissue transfers and in 1958 Bernard Seidenberg transferred a part of the jejunum to the esophagus to remove a cancer of the esophagus. Modern advancements in flap surgeries have continued since this time and are now commonly used in many procedures.