User:Emily438/Sickle cell trait

Article Draft
Sources

1. Johnson, Lena M. A Brief Historical Sketch of Sickle Cell Anemia in the African American Community, Southern University and Agricultural and Mechanical College, United States -- Louisiana, 2012''. ProQuest'', 7

“occurs in an unusual frequency in black populations and has been thought to originate as a by-product of African genetic adaptation to resist malaria.”

2. Kavanagh PL, Fasipe TA, Wun T. Sickle Cell Disease: A Review. JAMA. 2022;328(1):57–68. doi:10.1001/jama.2022.10233

“In the US, approximately 100,000 people have SCD, which is characterized by hemolytic anemia, acute and chronic pain, acute chest syndrome; increased incidence of stroke, nephropathy, and retinopathy; and a life span that is 20 years shorter than the general population.”

3.Coretta Jenerette, Marjorie Funk & Carolyn Murdaugh (2005) SICKLE CELL DISEASE: A STIGMATIZING CONDITION THAT MAY LEAD TO DEPRESSION, Issues in Mental Health Nursing, 26:10, 1081-1101, DOI: 10.1080/01612840500280745

“Depression may go untreated because of the stigma and high rates of disability associated with this chronic illness that most often affects African Americans in the United States.”

WHAT I ADDED "Another common side effect or symptom is depression especially if the disease is left untreated."

Mehak Stokoe, Hailey M. Zwicker, Caitlin Forbes, Nur E.L. Huda Abu-Saris, Taryn B. Fay-McClymont, Naddley Désiré, Gregory M.T. Guilcher, Gurpreet Singh, Michael Leaker, Keith Owen Yeates, K. Brooke Russell, Sara Cho, Tessa Carrels, Iqra Rahamatullah, Brianna Henry, Nicole Dunnewold, Fiona S.M. Schulte,

Health-related quality of life in children with sickle cell disease: A systematic review and meta-analysis, Blood Reviews, Volume 56,2022,100982, ISSN 0268-960X, https://doi.org/10.1016/j.blre.2022.100982.

This could be because they claim that children  “continue to be under-represented and under-researched compared to other pediatric chronic illness populations.” They do know that the pain is still very apparent and “debilitating.”