User:Emmaneary/sandbox

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 * Note: Please use your sandbox to submit assignment # 3 by pasting it below. When uploading your improvements to the article talk page please share your exact proposed edit (not the full assignment 3).


 * Talk Page Template: CARL Medical Editing Initiative/Fall 2019/Talk Page Template

Assignment # 2
'''Article: Cannabis Use Disorder

Information to add: Edibles'''

'''Search strategy and sources identified '''

“Edibles"[Mesh] AND "Cannabis Use”[Mesh] I selected the following filters: Article Types filter “review” and Dates flter “5 years” This search generated 3 articles I chose to review the following 2 articles:

1. Article 1

Russell, C., Rueda, S., Room, R., Tyndall, M. & Fischer, B. (2018). Routes of administration for cannabis use - basic prevalence and related health outcomes: A scoping review and synthesis. International Journal of Drug Policy, 52, 87-96.

This article was chosen because: This source is a review article. The information was reviewed directly by primary databases such as MEDLINE, EMBASE, PsycINFO and Google Scholar. This article is a secondary source (review article) and is recent (2018). Additionally, this journal was published in a well-established journal. The authors had not declared any conflicts of interest. The information provided relates directly to the topic, which is the comparison of various routes of administration for cannabis consumption. Although the most common routes includes smoking and tablets, consumption of “edibles” is poorly defined in the literature. I plan to include information from this source in the Wikipedia page relating to edibles, as the article cites important findings relating to the reduced health risks related to edible consumption in comparison with other routes of cannabis administration.

2. Article 2

Craven, C. B., Wawryk, N., Jiang, P., Liu, Z. & Li, X.F. (2019). Pesticides and trace elements in cannabis: Analytical and environmental challenges and opportunities. Journal of Environmental Sciences, 85, 82-93.

This article was chosen because: This article is a secondary source (review article) and is recent (2019). This journal was published in a well-established journal. The authors had not declared any conflicts of interest. This article is highly relevant, as it reviews the current analytical chall aenges discussed in other studies. The article reviewed a variety of credible primary studies, published recently in credible journals. The content of this review is highly relevant as it discusses the risk of contaminated cannabis. The article identifies contamination risks in various routes of administration. This information will be an important component of the “Edibles” Wikipedia section.�

Assignment # 3
Proposed Changes

Original: None. The proposed change is an addiction to the first portion of the “Signs and symptoms” paragraph.

New: The route of cannabis administration may pose different physical and psychological risk for cannabis dependency. Ingestion of “edibles” may increase the psychological ‘normalization’ of cannabis use, leading to an increased risk of dependency (1). Edible cannabis oils may contain residual solvents which cannot be reliably detected by current analytical methods (2). Residual solvent compounds introduce the risks of cancer, neurotoxicity and birth defects with chronic consumption (2).

Rationale: The original article does not discuss the psychological and physical health risks that are unique to chronic “edible” use. Unlike other routes of administration, “edible” use has fewer respiratory complications, and may, therefore, be perceived as a safe alternative. However, recent reviews have revealed that edible cannabis increases the risk of psychological normalization of cannabis consumption, which may lead to a cannabis use disorder. In addition to the psychiatric sequelae associated with cannabis abuse, “edibles” pose certain physical health risks. Recent reviews suggest that edible cannabis oils and products contain traces of carcinogenic, neurotoxic and teratogenic compounds that cannot be reliably detected by current analytical techniques. We propose that this section is added under the introduction of the “Signs and symptoms” section.

Critique of Source: Both sources were written in the past two years and are current. The sources reviewed a variety of credible primary studies and were published in well-established journals. Neither of the authors declared conflicts of interest. In the first review by Russell et al., it was stated that articles included in the search were “ English-language peer-reviewed publications” only. This English-language bias may have excluded various significant findings on routes of administration from other countries that could have impacted the conclusions in the review. As the number and relevance of articles spanned from a variety of English-speaking regions and no more impactful review articles are currently available, it is reasonable to rely on evidence from this paper. In the second article by Craven et al., the search strategy was not clearly described. Additionally, the paper alludes to the significant health risks posed by residual solvents but fails to provide a current source that focuses specifically on them. As this paper includes many credible sources that touch on residual solvents and the topic is not widely studied, it is reasonable to rely on evidence from this paper.

References:

1. Russell, C., Rueda, S., Room, R., Tyndall, M. & Fischer, B. (2018). Routes of administration for cannabis use - basic prevalence and related health outcomes: A scoping review and synthesis. International Journal of Drug Policy, 52, 87-96.

2. Craven, C. B., Wawryk, N., Jiang, P., Liu, Z. & Li, X.F. (2019). Pesticides and trace elements in cannabis: Analytical and environmental challenges and opportunities. Journal of Environmental Sciences, 85, 82-93.