User:EricBakota/Polygeny

Polygeny is the characteristic of having many genes of small effect and few genes of large effect contribute to a phenotype.

Polygeny is essential to the reconciliation of Mendelian genetics and population genetics.

Polygeny is a subcomponant of the concept of Genetic architecture.

Explain how polygenes can evolve.

Two major tools for uncovering polygeny. QTL mapping using linked traits and often times complex crosses.

Association mapping using inbred lines that have been fully sequenced. (See also, DGRP)

Bring up the statistical tools used for estimating QTLs.

Studies have found over 50% of the genome has a measurable affect on bristle count in drosophila. Look at studies dealing with variation in size, allometry, morphology.

Major references will be from Mackay and Falconer.