User:Erica Fiore

Name: Erica F., PhD Molecular Biologist with a PhD in Chemistry. Scientific communicator in the rare diseases field and scientist in the pre-clinical optimisation.

Education
2015-2016: Post-Doc at the University of Zürich, Zürich, Switzerland - Department of Chemistry, Prof. Dr. Roland K.O. Sigel. 2011-2015: PhD in Molecular and Chemical Sciences at the University of Zürich, Zürich, Switzerland - Department of Chemistry, Prof. Dr. Roland K.O. Sigel. Dissertation: “From Bulk to Single Molecule – Effects of Crowding Agents and Mutations on the Activity and Folding of a Group II Intron Ribozyme”. In this work, different techniques were used synergistically in order to characterize a large, catalytically active group II intron ribozyme. It was studied both the influence of molecular crowding on folding and function of a functional ribozyme variant and the folding pathway by generating and characterizing a number of mutants. While reading this work, I hope that you feel like I felt during these four years: enthusiastic and curious. 2009-2011: Master in Molecular Biology, University of Parma, Parma, Italy - Department of General and Inorganic Chemistry, Prof. Giorgio Pelosi, and Department of Physics, Section of Biophysics, Prof. Eugenia Polverini. Thesis title: "Thiosemicarbazones as inhibitors of ribonucleotide reductase: synthesis, characterization and preliminary studies of interaction with the enzyme". Degree in Molecular Biology cum laude.

Scientific Publications
2018: "Optimal molecular crowding accelerates group II intron folding and maximizes catalysis", PNAS 2018: "30 years for a diagnosis", checkorphan.wordpress.com 2017: "I don’t need a diet, I need a cure", checkorphan.wordpress.com 2017: "Takayasu’s Arteritis vs Chiara – 0:1", checkorphan.wordpress.com 2014: "Mimicking the in vivo Environment – The Effect of Crowding on RNA and Biomacromolecular Folding and Activity", Chimia 2013: "BOBA FRET: Bootstrap-Based Analysis of Single-Molecule FRET Data", PLOS ONE

Organizations
Nov 2018 - Present: Pint of Science, team of the city of Munich, Germany. Organization of scientific talks for a general audience. Feb 2016 – Present: UZH Alumni. Oct 2012 – Oct 2017: Swiss Volunteers. Staff/helper during sport events. 2012 - 2015: Swiss Chemical Society.

Certifications
GOOD CLINICAL PRACTICES, NIDA Clinical Trials Network (Feb 2017 – Feb 2020). Swiss Document of Personal Dosimetry, Dosimetric Passport (Schweizerische Persönliches Dosisdokument, Strahlenpass), Swiss Confederation. TELC German B1, telc GmbH - The European Language Certificates, TELC GmbH - The European Language Certificates.

Interest
Sport aficionado. Semi-professional athlete until 2011: 100m, 200m, 400m, 4x100m. Passion for scientific books.

Languages
Italian: mother tongue English: business fluent German: fluent French: basic

Awards
2014: Poster prize section Medicinal Chemistry & Chemical Biology at the Swiss Chemical Society Fall Meeting 2014. 2006: Oscar for merit in school and sport during High School.