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The Association of Trade and Commerce, co-founded by William Roach in 1921; the building was, from 1923 to 1956 at 2370 7th Avenue
 * 1925: John Edward Nail (1883–1947), President
 * 1926: Pope Barrow Billups (1889–1956), President
 * 1930: Junius M. Green (1876–1934), President
 * 1939: George W. Harris, President
 * 1941: George W. Harris, President (ex Alderman)
 * 1953: William R. Hudgins (1907–1972), President; Hudgins became President of Freedom National Bank around 1965
 * 1953: Benjamin E. Thomas, President Emeritus

The organization served as a clearinghouse for a number of civic and benevolent organizations in Harlem. The organization became dormant in 1959. In 1959, the National Business League moved in to the building at 2370 7th Avenue

Other commerce organizations founded in Harlem in the 1920s:


 * Colored Liquor Dealer's Association, founded 1912
 * New York Colored Business Men's Association, founded July 26, 1915; publisher of The Commercial Outlook; Richard E. Nicholas was the founding President


 * 1915: Lived at 44 W 135th (or business)

A. T. Anderson

Furniture dealer, 28 West 135th Street

J. Anderson

Arkonia Drug Store, 563 Lenox Avenue

A. O. Brambill

Tailor, 67 West 135th Street

C. Bush

Tailor, 103 West 138th Street

Richard E. Nicholas

Haberdasher, 72 West 135th Street

C. A. Sims

Laundry, 131 West 136th Street

R. J. Carr

Grocer, 29 West 135th Street

I. A. Weaver

Butcher, 517 Lenox Avenue

<li>L. P. Bailey

Royal Chemical Co., Station J, Box 36</li>

<li>R. S. Morgan

Real estate, 423 Lenox Avenue</li>

<li>Isaac Irvis

Tea & coffee, 36 West 133rd Street</li>

<li>C. W. Anderson

Butcher, 517 Lenox Avenue</li>

<li>E. Theodore Ashley

Tailor, 46 West 135th Street</li>

<li>W. H. Holly

Pharmacist, 2129 Madison Avenue</li>

<li>Lucius Jones

Tailor, 429 Lenox Avenue</li>

<li>Charles Kirnon

Grocer, 247 West 134th Street</li>

<li>Harold Kirnon

Grocer, 247 West 134th Street</li>

<li>Edward Manning

Sign painting, 34 West 185th Street</li>

<li>H. J. Thompson

Painter, 104 West 138th Street</li>

<li>Arthur Reid

West Indian Produce Co., 47 West 135th Street</li>

<li>T. C. Tabb

Lunch room saloon, 566 Lenox Avenue</li>

<li>C. L. Thorpe

Saloon, 66 West 135th Street</li>

<li>B. D. Wilkins

Saloon, 2275 Seventh avenue</li></ol>

Selected members

 * W. E. B. Du Bois