User:Evolutionary aging biologist

= Ohnologs (Database) = Ohnologs is a repository of the genes retained by the two rounds of whole genome duplications in six vertebrate genomes. The vertebrates currently included in Ohnologs are human, mouse, rat, chicken, pig and dog. The ohnolog pairs and families have been constructed using a quantitative multiple-genome comparative approach.

Importance of ohnologs
The genes retained from whole genome duplications are called ohnologs, after Susumu Ohno who proposed the importance of whole genome duplications in vertebrate evolution. Ohnologs in the human genome are known to be dosage balanced, and are frequently associated with cancers , dominant genetic diseases , and pathogenic copy number mutations.