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{Jeremy C Wyatt|Emeritus Professor of Digital Healthcare (University of Southampton, 2016)}

Professor Wyatt FACMI FFCI FIAHSI  (born 7  November 1954) is a British researcher in the fields of epidemiology and digital healthcare. Formerly at Dundee, Warwick and Leeds Universities and Director of the Wessex Institute of Health Research, he is now emeritus Professor of Digital Healthcare at the University of Southampton. He trained as a doctor at Oxford and London Universities (BA 1977, MB BS 1980; MRCP 1983, FRCP 1997, DM 1997), was Britain’s first elected Fellow of the American College of Medical Informatics (1997) and is a Founding Fellow of the Faculty of Clinical Informatics (2017) and the International Academy of Health Sciences Informatics (2018).

Early life and Education
Jeremy was born in Leamington Spa England and educated at Exeter School then Magdalen College School, Oxford. He studied for a BA of Physiology & Psychology at the University of Oxford in 1977 and a MB BS of Medicine and Surgery at the Medicine University of London in 1980. In 1983, he joined the Royal College of Physicians as member and completed a Doctorate of Medicine in Medical Informatics at the University of Oxford in 1992. He was elected fellow of the Royal College of Physicians in 1997.

Career
Professor Wyatt’s work falls into two distinct areas: clinical epidemiology and digital healthcare. In clinical epidemiology, his article Lancet series on medical knowledge in 1991 led to him convening and minuting the McMaster meeting in June 1992 that led to the founding of the international Cochrane Collaboration. He then founded the Cochrane Effective Practice and Organisation of Care review group in 1994. He was the first to automate the process of supporting RCT protocol writing in 1990 by developing a decision support tool, “Design-a-Trial”, to guide protocol authors based on Doug Altman’s knowledge [Comp Biomed Res 1994] and developed an RCT protocol ontology using PROTÉGÉ in 1998 [EPSRC funded]. As a member of Lucerne Study Group led by Wilfried Lorenz, he contributed to the first pre-published RCT protocol [Inflammation Res 2001]. He also co-authored the JAMA “User’s Guide to the Medical Literature” article on appraising reports of clinical decision support systems [JAMA 1998] and of chapters in the JAMA User’s Guide to the Medical Literature.

In digital healthcare, he was the first MRC-appointed Travelling Fellow in medical informatics, to Stanford University 1991-92. Much of his work has focused on decision support systems:


 * Designed and conducted the first randomised trial of clinical decision support in Europe, 1986 [MedInfo’89 paper]
 * Edited the first journal special issue on evaluation methods for decision support systems with Sir David Spiegelhalter, 1990 [Medical Informatics London]
 * Wrote an early article on legal aspects of decision support with Diana Brahams [Lancet 1989]
 * Identified automation bias as an issue in healthcare, co-supervised a PhD student who did the first systematic review and empirical study on this in 2010 [Refs]
 * The first to use a simulated decision-making experiment design to investigate the relative effectiveness and acceptability of alternative methods for delivering clinical advice [Scott 2011]
 * Collaborated on developing a new two-track model for decision support, taking account of behavioural knowledge as well as domain knowledge [Medlock, JAMIA 2018]
 * Proposed a collaboration between Royal Colleges, MHRA, NHS Digital and other arm’s length bodies to improve the safety of clinical decision support as part of an investigation into the QRisk2 incident, 2017
 * Investigated clinical trust in and concerns about decision support systems using mixed methods [Petkus 2019] and the O’Neill trust framework [Jones 2021]

Digital healthcare impact
Professor Wyatt has also actively promoted the development of digital healthcare as a discipline, including:
 * Developing a proposal for a UK national centre for health informatics [BMJ 1995] that became the UK Institute for Health Informatics with active local centres eg. YCHI, SIHI
 * Discovered the relevance of the information design discipline (on how to format information so it can be found fast and interpreted accurately), leading to a 4 article Lancet series on information design  [1998]; this was taken up by Microsoft UK for the NHS Common User Access guidance, 2005
 * Co-authored one of the first studies on the use of email for clinical consultations [JAMA 1998]
 * Originated the word “apptimism”, gave an early TeDx talk about problems with the accuracy & security of medical apps 2013 [link] and published an early checklist on how to reduce apptimism [Clinical Medicine 2015]
 * Originated the term “evidence-based informatics”, wrote the opening chapter of the Evidence-Based Health Informatics book 2017 [IOS press ref] and taught a tutorial on EBI at MIE Manchester [link]
 * Wrote the opening chapter in the Applied Interdisciplinary Theory in Health Informatics book 2019 [IOS Press ebook]
 * Promoted the importance of psychology and behaviour change as a basic science for digital healthcare from 2012 onwards, including delivering the keynote at the first annual conference of the UCL Centre for Behaviour Change, 2017 [link].
 * Introduced several novel evaluation methods to digital healthcare, eg. Wizard of Oz experiment, stated choice experiment, social network analysis, instrumental variable and regression discontinuity designs

To promote the digital healthcare discipline to others, Wyatt has: In his spare time he makes jewellery and commemorative objects in titanium: https://www.marlboroughopenstudios.co.uk/exhibiting-artists/jeremy-wyatt
 * Participated in the design and teaching of the UK’s first MSc programmes in health informatics at UCL 1993, City University, 1995 and Leeds 2012.
 * Co-authored with Charles Friedman the first textbook on evaluation methods in biomedical informatics 1996 (2nd edition 2005, 3rd edition to appear 2021)
 * Wrote the 2000 10-article JRSM series on medical knowledge and accompanying RSM Press book in 2001
 * Co-authored with Frank Sullivan the 12-article BMJ ABC of health informatics and accompanying book, BMJ 2005
 * Designed with Richard Giordano and delivered a WHO-sponsored course on health informatics for senior health system managers, Tehran 2018

Awards and honours
Other peer recognition includes:
 * Chair, European Society for AI in Medicine 1991-99
 * Elected Spinoza professor, Amsterdam, 2000
 * Member of the WHO Director General’s mHealth Technical Advisory Group, 2010-12
 * Member, Faculty of 1000 methodology panel 2012-2018
 * Found to be the third highest ranked academic in his field globally in a social network analysis, 2009 [Malin & Carley, JAMIA 2007]
 * 18260 citations to his publications with an H index of 59 [Google Scholar] – one of the top 5 in his field globally
 * Delivered 70 invited overseas talks and keynotes including at a NATO Advanced Research Workshop in Lucca 1990, the Diebold conference in Racine, Wisconsin 1993, a Council of Europe workshop in Germany 2008 and an invited WHO workshop at Rockefeller Bellagio, Italy 2014.
 * Appointed visiting professor in Oxford, Amsterdam and Oporto universities

Original Version
(7 November 1954)Jeremy C Wyatt FRCP FACMI FCI FIAHSI (born 1954 in Leamington Spa) is a British researcher in the fields of clinical epidemiology and digital healthcare. Formerly at Dundee, Warwick and Leeds Universities and Director of the Wessex Institute of Health Research [link], he is now emeritus Professor of Digital Healthcare at the University of Southampton. He trained as a doctor at Oxford and London Universities (BA 1977, MB BS 1980; MRCP 1983, FRCP 1997, DM 1997), was Britain’s first elected Fellow of the American College of Medical Informatics (1997) and is a Founding Fellow of the Faculty of Clinical Informatics (2017) and the International Academy of Health Sciences Informatics (2018). Other peer recognition includes:
 * Chair, European Society for AI in Medicine 1991-99
 * Elected Spinoza professor, Amsterdam, 2000
 * Member of the WHO Director General’s mHealth Technical Advisory Group, 2010-12
 * Member, Faculty of 1000 methodology panel 2012-2018
 * Found to be the third highest ranked academic in his field globally in a social network analysis, 2009 [Malin & Carley, JAMIA 2007]
 * 18260 citations to his publications with an H index of 59 [Google Scholar] – one of the top 5 in his field globally
 * Delivered 70 invited overseas talks and keynotes including at a NATO Advanced Research Workshop in Lucca 1990, the Diebold conference in Racine, Wisconsin 1993, a Council of Europe workshop in Germany 2008 and an invited WHO workshop at Rockefeller Bellagio, Italy 2014.
 * Appointed visiting professor in Oxford, Amsterdam and Oporto universities

Wyatt’s work falls into two distinct areas: clinical epidemiology and digital healthcare. In clinical epidemiology, his two-article Lancet series on medical knowledge in 1991 led to him convening and minuting the McMaster meeting in June 1992 that led to the founding of the international Cochrane Collaboration. He then founded the Cochrane Effective Practice and Organisation of Care review group in 1994. He was the first to automate the process of supporting RCT protocol writing in 1990 by developing a decision support tool, “Design-a-Trial”, to guide protocol authors based on Doug Altman’s knowledge [Comp Biomed Res 1994] and developed an RCT protocol ontology using PROTÉGÉ in 1998 [EPSRC funded]. As a member of Lucerne Study Group led by Wilfried Lorenz, he contributed to the first pre-published RCT protocol [Inflammation Res 2001]. He also co-authored the JAMA “User’s Guide to the Medical Literature” article on appraising reports of clinical decision support systems [JAMA 1998] and of chapters in the JAMA User’s Guide to the Medical Literature.

In digital healthcare, he was the first MRC-appointed Travelling Fellow in medical informatics, to Stanford University 1991-92. Much of his work has focused on decision support systems:


 * Designed and conducted the first randomised trial of clinical decision support in Europe, 1986 [MedInfo’89 paper]
 * Edited the first journal special issue on evaluation methods for decision support systems with Sir David Spiegelhalter, 1990 [Medical Informatics London]
 * Wrote an early article on legal aspects of decision support with Diana Brahams [Lancet 1989]
 * Identified automation bias as an issue in healthcare, co-supervised a PhD student who did the first systematic review and empirical study on this in 2010 [Refs]
 * The first to use a simulated decision-making experiment design to investigate the relative effectiveness and acceptability of alternative methods for delivering clinical advice [Scott 2011]
 * Collaborated on developing a new two-track model for decision support, taking account of behavioural knowledge as well as domain knowledge [Medlock, JAMIA 2018]
 * Proposed a collaboration between Royal Colleges, MHRA, NHS Digital and other arm’s length bodies to improve the safety of clinical decision support as part of an investigation into the QRisk2 incident, 2017
 * Investigated clinical trust in and concerns about decision support systems using mixed methods [Petkus 2019] and the O’Neill trust framework [Jones 2021]

He has also actively promoted the development of digital healthcare as a discipline, including:
 * Developing a proposal for a UK national centre for health informatics [BMJ 1995] that became the UK Institute for Health Informatics with active local centres eg. YCHI, SIHI
 * Discovered the relevance of the information design discipline (on how to format information so it can be found fast and interpreted accurately), leading to a 4 article Lancet series on information design  [1998]; this was taken up by Microsoft UK for the NHS Common User Access guidance, 2005
 * Co-authored one of the first studies on the use of email for clinical consultations [JAMA 1998]
 * Originated the word “apptimism”, gave an early TeDx talk about problems with the accuracy & security of medical apps 2013 [link] and published an early checklist on how to reduce apptimism [Clinical Medicine 2015]
 * Originated the term “evidence-based informatics”, wrote the opening chapter of the Evidence-Based Health Informatics book 2017 [IOS press ref] and taught a tutorial on EBI at MIE Manchester [link]
 * Wrote the opening chapter in the Applied Interdisciplinary Theory in Health Informatics book 2019 [IOS Press ebook]
 * Promoted the importance of psychology and behaviour change as a basic science for digital healthcare from 2012 onwards, including delivering the keynote at the first annual conference of the UCL Centre for Behaviour Change, 2017 [link].
 * Introduced several novel evaluation methods to digital healthcare, eg. Wizard of Oz experiment, stated choice experiment, social network analysis, instrumental variable and regression discontinuity designs

To promote the digital healthcare discipline to others, Wyatt has: In his spare time he makes jewellery and commemorative objects in titanium: https://www.marlboroughopenstudios.co.uk/exhibiting-artists/jeremy-wyatt
 * Participated in the design and teaching of the UK’s first MSc programmes in health informatics at UCL 1993, City University, 1995 and Leeds 2012.
 * Co-authored with Charles Friedman the first textbook on evaluation methods in biomedical informatics 1996 (2nd edition 2005, 3rd edition to appear 2021)
 * Wrote the 2000 10-article JRSM series on medical knowledge and accompanying RSM Press book in 2001
 * Co-authored with Frank Sullivan the 12-article BMJ ABC of health informatics and accompanying book, BMJ 2005
 * Designed with Richard Giordano and delivered a WHO-sponsored course on health informatics for senior health system managers, Tehran 2018

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