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The Holographic Bubble Chamber, HOBC, was a heavy-liquid rapid-cycling bubble chamber.

Bubble chambers are similar to cloud chambers, both in application and in basic principle. A chamber is normally made by filling a large cylinder with a liquid heated to just below its boiling point. As particles enter the chamber, a piston suddenly decreases its pressure, and the liquid enters into a superheated, metastable phase. Charged particles create an ionization track, around which the liquid vaporizes, forming microscopic bubbles. Bubble density around a track is proportional to a particle's energy loss. Bubbles grow in size as the chamber expands, until they are large enough to be seen or photographed. Several cameras are mounted around it, allowing a three-dimensional image of an event to be captured.

HOBC was a small (2 l) heavy-liquid rapid-cycling bubble chamber which was designed specifically for the use of in-line holography for the CERN experiment NA25.