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Solaris Biotech Solutions
Solaris Biotech Solutions is an Italian company specializing in fermenters, bioreactors and filtration systems for R&D and production purposes. The company offers high-tech solutions within the reach of both the student and the experienced user alike.

Solaris' products are used in universities, schools and research centers, as well as in pharmaceutical, nutraceutical, cosmeceutical, chemical, agricultural, and food and beverage industries, not to mention bioplastics and biofuels applications.

Solaris operates internationally through production sites in Italy, operating offices in the USA (Berkeley in California and Cambridge in Massachusetts), in Malaysia (Kuala Lumpur) and its sales specialists around the world.

Solaris is today part of the Donaldson Company, a vertically integrated filtration company engaged in the production and marketing of air filters used in a variety of industry sectors, including commercial/industrial (engines, exhausts, transmissions, vents in private vehicles, hydraulics), aerospace (helicopters, planes), chemical, alternative energy (windmills) and pharmaceuticals.

History
Solaris was founded in 2002 in Mantua, in the North of Italy, started exploring Industrial manufacturing of fermentation and filtration systems, committed to totally customizable cGMP pilot-industrial equipment and to the design and manufacturing of full turnkey solutions.

The company was founded by Matteo Brognoli and Cristiano Pecchini to offer the tools for the production and scale up of biotechnological processes. Matteo Brognoli, co-founder and Managing Director, has been leading the business of Solaris for more than 20 years, currently covering the role of General Manager of Bioprocess Equipment for Donaldson Life Sciences globally.

The company is known as Solaris Biotech Solutions for the activity and commitment in the world of biotechnologies.

Solaris Biotechnology Srl is the parent company founded next to the first branch Solaris Industrial Srl, specialized in Industrial Production. The second subsidiary, Solaris Lab Srl, was born in 2018 and allowed to expand the fields of application of company production.

Solaris Lab is dedicated to laboratory scale fermenters and filtration equipment from 120ml up to 20L, mainly serving the needs of Research & Development and academia.

Between 2019 and 2020 the company decides to opening the first American branch Solaris Biotech USA, Inc., in Berkely (CA), with an operative office and a showroom right next to the San Francisco Bay Area. Secondly, by opening an APAC division with a sales and technical office in Kuala Lumpur, Malaysia.

In November 2021, Solaris has been acquired by the Donaldson Company.

In October 2022 the company has announced the opening of a second operating office for its US branch, located at the CIC co-working space in the center of Kendall Square in Cambridge (MA).

Divisions and Subsidiaries
Solaris HQ and production sites


 * Solaris Biotechnology Srl and Solaris Industrial Srl, with two facilities located in Mantua, Italy dedicated to the Industrial manufacturing of equipment and plants.
 * Solaris Lab Srl, dedicated to the Laboratory division production and having its production site next to the Industrial production in Mantua.

Solaris Biotech USA, Inc.


 * Solaris Biotech USA, Inc. in Berkeley, with a commercial office and showroom near to the San Francisco Bay Area.
 * Solaris Biotech USA, Inc. in Cambridge, with a commercial office and showroom in Kendall Square, in Cambridge (MA).

Solaris APAC


 * APAC Division, with a commercial office and showroom in Kuala Lumpur in Malaysia.

Application fields
Biotech and Pharma


 * Antibiotics, Antitumorals, Human Vaccines, APIs, Hormones, Non-addictive Pain Killers, Monoclonal Antibodies.

Food & Beverage


 * Meat/cheese/wine starters, Meat Preservatives, Cellular Agriculture, Flavors, Plant-based substitutes for meat products, Low Carb Drinks, Fermented Drinks.

Nutraceutical


 * Dietary supplements, Food additives.

Cosmeceutical


 * Bioactive ingredients, Hyaluronic Acid, Q10 Coenzime.

Chemical & Biofuels


 * Additives, Reagents, Refined commodities, Olefins.

Bioremediation


 * All microorganisms (bacteria, fungi, yeasts, algae) with the ability to modify toxic species.

Animal Health and Nutrition


 * Veterinary vaccines, Animal feeding and supplements.

Agriculture


 * Biofertilizers, Biopesticides, Algae Fertilizer.

Biomaterials


 * Biopolymers, Bioplastics.

Scientific Publications

 * Amaretti 2007 in Applied and Environmental Microbiology, “Kinetics and Metabolism of Bifidobacterium adolescentis MB 239 Growing on Glucose, Galactose, Lactose, and Galactooligosaccharides” using a Solaris’ Jupiter model.
 * Dellomonaco 2007 in J Ind Microbiol Biotechnol, “Fermentative production of superoxide dismutase with Kluyveromyces marxianus” using a Solaris’ Jupiter model.
 * DiGioia 2007 in Enzyme and Microbial Technology, “Production of biovanillin from wheat bran” using a Solaris’ Jupiter model.
 * Van Herdeen 2013 in Microbial Cell Factories, “Continuous and batch cultures of Escherichia Coli KJ134 for succinic and acid fermentation: metabolic flux distributions and production characteristics” using a Solaris’ Jupiter model.
 * Jaya Prakash 2014 in Journal of Pharmaceutical and BioSciences, “Preparation, Characterization and In Vitro Evaluation of Novel Gellan Gum-Raloxifene HCl Nanoparticles” using a Solaris’ Jupiter model.
 * Kringe 2015 in Process Biochemistry, “Continuous succinic acid fermentation by Escherichia coli KJ122 with cell recycle” using a Solaris’ Jupiter model.
 * Tamburini 2015 in Biomolecules, “Optimized Production of Xylitol from Xylose Using a Hyper-Acidophilic Candida tropicalis” using a Solaris’ Jupiter model.
 * Gargano 2016 in New Biotechnology, “Alkaline direct transesterification of different species of Stichococcus for bio-oil production” using a Solaris’ Metis Gas Analyzer model.
 * Shi 2018 in Chemical Engineering Science, “Manipulating the generation of reactive oxygen species through intermittent hypoxic stress for enhanced accumulation of arachidonic acid-rich lipids” using a Solaris’ IO1000 model.

Certifications and Validations
Good Manufacturing Practices:

Solaris offers Good Manufacturing Practices (GMPs and cGMPs) certifications. According to the World Health Organization, the GMP system concerns itself with and certifies all aspects of production: from raw materials, premises and equipment used, to training and personal hygiene of all workers and so describe the minimum standard that a drug manufacturer must adhere to in all the manufacturing processes.

The GMPs are applied to the sense of Title 21 Code of Federal Regulations and can be described, coherently to the Title, in a different connotation in each country.

IQ, OQ and PQ protocols:

Solaris offers protocols of methods for demonstrating that the equipment being used or installed will offer a high degree of quality assurance such that production processes will consistently manufacture products that meet quality requirements.

Installation Qualification (IQ) verifies that an instrument or unit of equipment being qualified (as well as its sub-systems and any ancillary systems) has been installed and configured according to the manufacturer’s specifications or installation checklist.

Operational Qualification (OQ) involves testing the equipment to assure it performs as specified, within operating ranges as listed by the manufacturer. All aspects of the equipment receive individual testing and the tester documents the proper operation of each.

Performance Qualification (PQ) is the final step of qualifying equipment. In this phase, the protocol will feature verification and documentation that all equipment is working within the accepted range as specified, does it perform as expected under real conditions. All instruments are tested together according to a detailed test plan and must generate reproducible results.

Awards
2020 – Top food packaging and processing tech solution providers by Food & Beverage technology review

2022 – The building blocks of alternative proteins: the 40 startups providing the infrastructure to make animal-free protein a reality by FoodHack