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Wenxin Keli (WXKL) is Chinese herb extract composed of Nardostachys chinensis Batal extract, Codonopsis, notoginseng, amber, and rhizoma polygonati. Wenxin Keli has been used to treat congestive heart failure (CHF) and arrhythmia. In animal studies, Wenxin Keli has produced effects more noticeable in arterial tissue than in ventricular tissue.

A meta-analysis concluded that Wenxin Keli alone or in combination with other anti-arrhythmics decreases the recurrences artial fibrillation in patients with paroxysmal atrial fibrillation. Trials used in the meta-analysis reported some adverse events, indicating that the safety of WXKL is still uncertain. .

Wenxin Keli was developed by Guang’anmen Hospital, Chinese Academy of Chinese Medical Sciences.