User:Fuzzform/ProjectAntiObesity

This list excludes common OTC diet products. See the talk page for relevant info for each drug.

Antiobesity preparations

 * Centrally acting antiobesity products


 * Phentermine
 * IUPAC: 2-methyl-1-phenyl-propan-2-amine
 * ATC: A08 AA01
 * CAS: 122-09-8
 * Pubchem: 4771
 * DrugBank: APRD00093
 * MW: 149.233
 * MF: C10H15N
 * Protein binding: Approximately 96.3%
 * Metabolism: Hepatic
 * Half-Life: 16 - 31 hours
 * LD50: 15 to 20 mg/kg (in adult monkeys)
 * Overdose symptoms: delirium, mania, self-injury, hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, circulatory collapse
 * Classification: Adrenergic Agents, Appetite Depressants, Central Nervous System Agents, Anorexigenic Agents, Stimulants
 * RxList.com: http://www.rxlist.com/cgi/generic/phenterm.htm
 * Inchem.org: http://www.inchem.org/documents/pims/pharm/pim415.htm


 * Fenfluramine


 * Amfepramone (Diethylpropion, Diethylpropione)
 * IUPAC: 2-diethylamino-1-phenyl-propan-1-one
 * ATC: A08 AA03
 * CAS: 134-80-5
 * Pubchem: 7029
 * DrugBank: APRD00919
 * MW: 205.296
 * MF: C13H19NO
 * Metabolism: See talk page.
 * Half-Life: 4 - 6 hours
 * LD50: 600 mg/kg (for mice), 250 mg/kg (for rats), 225 mg/kg (for dogs)
 * Overdose symptoms: restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states
 * Classification: Appetite Depressants, Anorexigenic Agents, Stimulants
 * RxList.com: http://www.rxlist.com/cgi/generic3/diethprop.htm
 * Inchem.org: http://www.inchem.org/documents/pims/pharm/pim937.htm


 * Dexfenfluramine
 * IUPAC: N-ethyl-1-[3-(trifluoromethyl)phenyl]-propan-2-amine
 * ATC: A08 AA04
 * CAS: 3239-44-9
 * Pubchem: 66264
 * DrugBank: APRD00648
 * MW: 231.257
 * MF: C12H16F3N
 * Protein binding: 36%
 * Metabolism: See talk page.
 * Half-Life: 17-20 hours
 * Classification: Serotonin reuptake inhibitors, Antiobesity Agents, Appetite Depressants
 * RxList.com: http://www.rxlist.com/cgi/generic/dexfen.htm
 * Inchem.org: http://www.inchem.org/documents/pims/pharm/pim939.htm


 * Mazindol
 * IUPAC: ???
 * ATC: A08 AA05
 * CAS: 22232-71-9
 * Pubchem: 4020
 * DrugBank: APRD01085
 * MW: 284.740
 * MF: C16H13ClN2O
 * Metabolism: Hepatic
 * Half-Life: 10-13 hours
 * Overdose symptoms: restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, seizures
 * Classification: Adrenergic Uptake Inhibitors, Central Nervous System Stimulants, Dopamine Uptake Inhibitors
 * RxList.com: http://www.rxlist.com/drugs/drug-6095-Mazindol+Oral.aspx?drugid=6095&drugname=Mazindol+Oral


 * Etilamfetamine
 * IUPAC: N-ethyl-1-phenyl-propan-2-amine
 * ATC: A08 AA06
 * CAS: ???
 * Pubchem: 9982
 * DrugBank: N/A
 * MW: 163.259
 * MF: C11H17N


 * Cathine (Norephedrine)
 * IUPAC: 2-amino-1-phenyl-propan-1-ol
 * ATC: A08 AA07
 * CAS: ???
 * Pubchem: 4786
 * DrugBank: N/A
 * MW: 151.206
 * MF: C9H13NO


 * Clobenzorex
 * IUPAC: N-[(2-chlorophenyl)methyl]-1-phenyl-propan-2-amine
 * ATC: A08 AA08
 * CAS: ???
 * Pubchem: 71675
 * DrugBank: N/A
 * MW: 259.774
 * MF: C16H18ClN


 * Mefenorex (Anexate, Pondinil, Rondimen)
 * IUPAC: N-(3-chloropropyl)-1-phenyl-propan-2-amine
 * ATC: A08 AA09
 * CAS: ???
 * Pubchem: 21777
 * DrugBank: N/A
 * MW: 211.731
 * MF: C12H18ClN


 * Sibutramine
 * IUPAC: 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine
 * ATC: A08 AA10
 * CAS: 106650-56-0
 * Pubchem: 5210
 * DrugBank: APRD00456
 * MW: 279.848
 * MF: C17H26ClN
 * Bioavailability: 77%
 * Protein binding: 97%
 * Metabolism: Hepatic
 * Half-Life: 1.1 hours
 * Side effects: dry mouth, anorexia, insomnia, constipation and headache
 * Classification: Appetite Depressants, Antidepressants, Anorexigenic Agents, Stimulants
 * RxList.com: http://www.rxlist.com/cgi/generic/sibutramine.htm


 * Other antiobesity products
 * Ephedrine
 * IUPAC:
 * ATC: A08 AA56
 * CAS:
 * Pubchem:
 * DrugBank:
 * MW:
 * MF:
 * Protein binding:
 * Metabolism:
 * Half-Life:
 * LD50:
 * Overdose symptoms:
 * Classification:
 * RxList.com:
 * Inchem.org:


 * Orlistat
 * IUPAC:
 * ATC: A08 AB01
 * CAS:
 * Pubchem:
 * DrugBank:
 * MW:
 * MF:
 * Protein binding:
 * Metabolism:
 * Half-Life:
 * LD50:
 * Overdose symptoms:
 * Classification:
 * RxList.com:
 * Inchem.org: