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Article Evaluation

Evolutionary developmental biology

Some unvalidated claims in the introduction: "Another possibility is the Neo-Lamarckian theory that epigenetic changes are later consolidated at gene level, something that may have been important early in the history of multicellular life." - no citation

Possible Bias: This multiple pleiotropic reuse explains why these genes are highly conserved, as any change would have many adverse consequences which natural selection would oppose.