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Diet and lifestyle are major factors that are thought to influence susceptibility to many diseases. Drug abuse, tobacco smoking, and alcohol drinking, as well as a lack of or too much exercise may also increase the risk of developing certain diseases, especially later in life.

In many Western countries, people began to consume more meat, dairy products, vegetable oils, tobacco, sugary foods, sugary beverages, and alcoholic beverages during the latter half of the 20th century. People also developed sedentary lifestyles and greater rates of obesity. Rates of colorectal cancer, breast cancer, prostate cancer, endometrial cancer and lung cancer started increasing after this dietary change. People in developing countries, whose diets still depend largely on low-sugar starchy foods with little meat or fat have lower rates of these cancers. Causes are not just from smoking and alcohol abuse. Adults can develop lifestyle diseases through behavioral factors that impact on them. These can be unemployment, unsafe life, poor social environment, working conditions, stress and home life can change a person’s lifestyle to increase their risk of developing one of these diseases