User:Gomezestro/sandbox

Specific Populations

 * Geriatric: Use of meloxicam is not recommended in patients with peptic ulcer disease or increased gastrointestinal bleed risk, including those over 75 years old or taking medications associated with bleeding risk. Adverse events associated with meloxicam have been found to be associated with length of treatment and dose-dependent.
 * Pediatric:
 * Gender:
 * Kidney impairment:
 * Hemodialysis:
 * Hepatic impairment:

Absorption
The absolute bioavailability of oral meloxicam is 89% compared to intravenous bolus injection of the same dose. Food has no effect on systemic availability, except in its SoluMatrix capsule formulation that maintained a bioequivalent AUC.

Distribution
Meloxicam extensively binds to plasma proteins, with a marginal decrease in binding seen in patients with renal disease