User:Gronostajski

Richard M. Gronostajski, Ph.D., is a Professor of Biochemistry at the University at Buffalo (UB), Founder and Head of the Developmental Genomics Group at the New York State Center of Excellence in Bioinformatics and Life Sciences and Director of both the Western New York Stem Cell Culture and Analysis Center and the Genetics, Genomics and Bioinformatics Graduate Program at UB. He also holds an adjunct faculty position in the department of Molecular and Cellular Biology at Roswell Park Cancer Institute. Dr. Gronostajski received his B.Sc. and M.Sc. in Biochemistry from Virginia Polytechnic Institute and State University and his Ph.D. in Physiology from Harvard University. His doctoral studies investigated the role of intracellular proteolysis on cell cycle regulation and his postdoctoral work at the Albert Einstein College of Medicine and the University of Toronto addressed mechanisms of adenovirus and cellular DNA replication and mechanisms of FLP-mediated site-specific recombination, respectively.

Prior to joining UB in 2001 he held academic positions in the Ontario Cancer Institute and University of Toronto department of Medical Biophysics (1985-92) and in the Cleveland Clinic Foundation Lerner Research Institute department of Cancer Biology and Case Western Reserve University department of Biochemistry (1992-2001). He is a member of AAAS, the ISSCR and the Society for Developmental Biology and has performed reviews for various journals, the NIH and the Wellcome Trust. He has authored over 100 peer-reviewed articles, most on the role of the Nuclear Factor I (NFI) transcription factors in animal development. His laboratory uses mouse Embryonal Stem Cells to generate mutant mice for studying lung and brain development and is currently investigating the role of Nfib in fetal and postnatal lung development and the role of Nfix in adult neural stem cell homeostasis.