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= C2orf72 = Chromosome 2 open reading frame 72 (c2orf72) is a protein that in humans is encoded by the gene c2orf72. The function of this protein is currently unknown.

Gene
This gene consists of 3,629 nucleotides, contains 3 exons and 2 introns, and the protein it encodes is 295 amino acids long.

It has orthologs in a number of different organisms, including mice, dogs, fish, frogs, chickens, snakes, and many others. C2orf72 has no known isoforms.

Location
This gene is located in the human genome at 2q37.1. Its transcript contains 3,629 nucleotides, and has 3 exons.

Expression
On average, the most abundant tissues for gene c2orf72 are the liver and brain, while the abundance in the placenta has the potential to be quite high. During the developmental phase, the gene is most prevalent in the intestine and stomach. In the brain, it is found primarily in the cingulate cortex.

Primary Sequences
The protein C2orf72 is 295 amino acids long. It has an experimental molecular weight of 38 kDa. It is predicted to be located in the cytoplasm. There is a high amount of alanine and arginine relative to other proteins, as they make up 22.4% and 11.5% of the amino acids in the protein respectively.

Post-Translational Modifications
The protein contains both a globular domain and a section of high disorder. It contains no trans-membrane regions.

Secondary Structure and Tertiary Structure
The predicted secondary structure of c2orf72 consists primarily of alpha helices, with significant coiling in the final 30 amino acids.

Paralogs
No paralogs exist for protein c2orf72. There is one paralogous domain found in hCG1777421.

Distant Homologs
The most distant homolog discovered is the Mangrove Rivulus.