User:HRShami/Christopher Kane (academic)

Christopher Kane is an American urologist, researcher and educator. He is the Dean of Clinical Affairs at University of California San Diego and CEO of UCSD Health Physician Group. He is also a Professor and Joseph D. Schmidt MD Presidential Chair in Urology at UCSD. He is a member executive of Governing Body UCSD Health Sciences and a member of Executive Committee of UCSD Clinical Integration Network.

Kane's research is focused on prostate cancer prognosis, renal cell carcinoma prognosis and minimally invasive therapy for urologic diseases. A significant part of his research deals with surgical innovation including laparoscopic surgery and robotic surgery. Kane has authored more than 320 publications and book chapters.

Kane was elected to the American Association of Genitourinary Surgeons in 2014 and Clinical Society of Genitourinary Surgeons in 2017. He was awarded the Distinguished Engineering Alumni Medal by University of California, Davis in 2011.

Education
Kane received a BS in Mechanical Engineering from University of California, Davis in 1985 and an MD from Uniformed Services University of the Health Sciences in 1989. Subsequently, he completed his residency at UC Davis East Bay, Oakland Naval Medical Center and University of California, San Francisco.

Career
In 1995, Kane joined USUHS, Naval Medical Center as a Clinical Instructor of Surgery, becoming Assistant Professor in 1999. From 1995 to 2001, he was the Urology residency director at the Naval Medical Center in San Diego (NMCSD). He was also the Surgeon General’s Advisor for Urology from 1998 to 2001. At that time he became a principal investigator of the Center for Prostate Disease Research, the military prostate cancer database. He organized the contribution of the data from the NMCSD and began his prostate cancer outcomes research collaboration. Significant contributions of CPDR manuscripts of that era were an understanding of the impact of socioeconomic status on prostate cancer risk and outcomes as well as an understanding of African American race on biochemical recurrence, risk stratification and outcomes, and investigations into the relationship of race and obesity in prostate cancer outcomes. Kane co-authored 14 publications related to that collaboration.

In 2001, Kane left Naval Medical Center and joined University of California San Francisco (UCSF) as an Associate Professor of Surgery. At the same time, he was appointed as the Chief of Urology at Veterans Affairs Medical Center, San Francisco, and served in this position until 2007. He briefly served as the Vice Chairman of Department of Urology at UCSF from 2006 to 2007. Kane then joined the faculty at UCSF, where he was Division Chief at the VAMC San Francisco and practiced at the UCSF Comprehensive Cancer Center from 2001 to 2007.

Kane left UCSF and moved to University of California San Diego as Professor of Surgery and Direct of Urology Residency Program and served in this position until 2014. During this time, he also served as the Chief of Division of Urology. Urology became a clinical department in 2013 and became a new academic department at UCSD in 2017 with Kane as the founding Chair.

In 2008, Kane was appointed as the Director of Robotic Surgery and UCSD Health System and in 2013, the Chair of Department of Urology and UC San Diego Health. From 2008 to 2013, Kane was the Genitourinary Oncology Team Leader, UCSD Moores Comprehensive Cancer Center and later served as the Senior Deputy Director of the Center. In 2015, he was endowed the Joseph D. Schmidt MD Presidential Chair in Urology.

Kane has also had a career in the military since 1985. From 2001 to 2005, he was Commander in the United States Navy Reserve and From 2005 to 2009, he was Captain in Medical Corps, before retiring.

He serves on the editorial boards of many scientific journals including Urologists in Cancer Care, The American Journal of Hematology/Oncology, World Journal of Urology and Prostate Cancer and Prostatic Diseases.

Research and work
Kane's research interests are primarily prostate cancer and kidney cancer risk assessment and outcomes. A significant part of his research deals with surgical innovation including laparoscopic surgery and robotic surgery. His research has involved three of the largest multi-center databases, the CPDR military database, the CaPSURE database, and the SEARCH database.

Since the beginning of his research career, Kane's work has been focused on prostate cancer, its treatment and prognosis. Initially, in the early and mid 1990s, his work in this area was focused on prognosis and imaging of prostate cancer. Towards the late 1990s, he began conducting research on treatments for prostate cancer. He wrote papers on transurethral prostatectomy, live donor nephrectomy and urethral reconstruction. The work on prostate cancer prognosis continued well into the late 2010s. Beginning in 2004, he wrote several papers on the use of Saw Palmetto for treating prostate cancer. His 2006 paper, entitled 'Saw palmetto for benign prostatic hyperplasia' published in New England Journal of Medicine has been cited over 500 times and explains...

In the early 2000s, Kane began studying how obesity can impact the likelihood of prostate cancer and the prognosis after treatment. Beginning in 2000s, he has also written considerably about genetic markers, CpG island hypermethylation and T-Cell functions in prostate cancer. In 2015, he wrote the paper, The molecular taxonomy of primary prostate cancer. Published in Cell, the paper discusses...

In 2004, Kane wrote the paper Are There Differences in Complications and Outcomes for Obese Patients Receiving Laparoscopic Nephrectomy?, which marked the beginning of his research on laparoscopic surgery and robot assisted surgery. Since the early 2000s, Kane has also written significant about radical prostatectomy.

In 2000, he wrote the paper 'Impact of socioeconomic status and race on clinical parameters of patients undergoing radical prostatectomy in an equal access health care system'. This led to several papers on how race and ethnicity can impact likelihood of prostate cancer and prognosis afterwards.

In early 2010s, Kane's research began focusing on fluorescence based imaging where he has written several papers with David Vera. His cross-disciplinary work in this area produced an important publication in 2017. Along with the work on fluorescence based imaging, Kane also started focusing on MRI towards the mid-2010s. In this area, with Donna Hansel and David Karow, he was awarded a Prostate Cancer Foundation Challenge Award for the project 'Evaluation of Whole Body RSI-MRI as a Biomarker for Detection, Characterization and Therapy Response of Metastatic Prostate Cancer'.

Kane is a founding member of the SEARCH database, a multi-center collaboration of surgical outcomes of men with prostate cancer treated at six VA medical centers. Kane contributed to 128 manuscripts across a wide variety of topics including the impact of PSA density and PSA velocity in risk stratification, and after recurrence, the utility of imaging and salvage treatments for various populations of patients. This series of investigations includes risk factors for success of androgen deprivation therapy and predictors of metastases and the utilities of various forms of treatment for advanced disease. Significant contributions concerning low-risk prostate cancer and the appropriateness of active surveillance for various populations were also made in this group. And the most precise predictions of the impact of race on outcomes, recurrence, and the success of salvage treatment have been made using the SEARCH database. '

Awards and honors

 * 1994 - Resident Scholarship Award Recipient, 70th Annual Meeting, Western Section, American Urological Association
 * 1998 - Pfizer Scholars in Urology Award, Naval Medical Center, San Diego
 * 2010 - Physician Healthcare Champion of the Year for San Diego, San Diego Business Journal
 * 2011 - Distinguished Engineering Alumni Medal, UC Davis College of Engineering

Military awards

 * 1990 - Humanitarian Service Medal
 * 1990 - Navy Achievement Medal (Outstanding Surgical Intern)
 * 1991 - Navy Commendation Medal (Operation Desert Storm)
 * 1991 - Combat Action Ribbon (Operation Desert Storm)
 * 1991 - Navy Unit Commendation Medal (Operation Desert Storm)
 * 1991 - Navy Fleet Marine Force Service Ribbon
 * 1991 - South East Asia Service Medal
 * 1991 - Kuwait Liberation Medal (Operation Desert Storm)
 * 1991 - National Defense Ribbon
 * 1991 - Sea Service Deployment Medal
 * 1991 - Navy-Marine Corps Overseas Service Ribbon
 * 2000 - Navy Commendation Medal (Star in lieu of second award)
 * 2001 - Meritorious Service Medal
 * 2003 - Armed Forces Reserve Medal with M Device
 * 2003 - National Defense Ribbon (Star in lieu of second award)
 * 2009 - Navy Commendation Medal (Star in lieu of third award)

Book chapters

 * Kane CJ, Stoller ML, Grossfeld GD. Laparoscopic radical prostatectomy. In Carroll PR and Grossfeld GD, eds. Prostate Cancer. American Cancer Society Atlas of Clinical Oncology Series. Hamilton, Ontario: BC Decker; 2002: chap 14; 207.
 * Kane CJ. Disorders of the adrenal glands. In Tanagho EA, McAninch JW, eds. Smith’s General Urology. 16th ed. New York, NY: Lange Medical Books/McGraw-Hill; 2004: chap 29.
 * Yun EJ, Kane CJ. Renal artery embolism and renal vein thrombosis. In Wessells H, McAninch JW, eds. Urological Emergencies: A Practical Guide. Totowa, NJ: Humana Press; 2005: chap 11; 171.
 * Kane CJ. Treatment of ureteral stones. In Smith AD, Bagley D, et al, eds. Smith’s Textbook of Endourology. 2nd ed. Hamilton, Ontario: BC Decker; 2006: chap 18.
 * Stoller ML, Kane CJ, Carroll PR. Urology. In McPhee S, Papadakis MA, Tierney LM Jr, eds. Current Medical Diagnosis and Treatment 2007. Stamford, CN: Appleton & Lange; 2007.
 * Kane CJ. Conservative management of ureteral calculi. In Stoller ML, Meng MV, eds. Urinary Stone Disease: The Practical Guide to Medical and Surgical Management. Totowa, NJ: Humana Press; 2007: chap 24. Klein EA, ed. Current Clinical Urology Series.
 * Kane CJ, Tanagho EA. Specific infections of the genitourinary tract. In Tanagho EA, McAninch JW, eds. Smith’s General Urology. 17th ed. New York, NY: Lange Medical Books/McGraw-Hill; 2008: chap 14.
 * Kane CJ. Disorders of the adrenal glands.  In Smith’s General Urology, 17th ed., eds Tanagho EA and McAninch JW.  New York: Lange Medical Books/McGraw-Hill; 2008: chap 30.
 * Stoller ML, Kane CJ, Meng, MV. Urologic Disorders. In McPhee S, Papadakis MA, Tierney LM Jr, eds. Current Medical Diagnosis and Treatment 2008. Stamford, CN: Appleton & Lange, 2008.
 * Kane CJ, Advisory Board for Smith RP, Turek PJ, ed. The Netter Collection of Medical Illustrations: Reproductive System. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2011
 * Breyer BN, Kane CJ. Ureteral Stricture. eMedicine from WebMD. Updated January 23, 	2012. http://emedicine.medscape.com/article/442469-overview.
 * Woo JR, Yun EJ, Kane CJ. Renal artery embolism and renal vein thrombosis. In Wessells 	H, ed. Urological Emergencies: A Practical Approach Current Clinical Urology. New York, 	NY: Springer Science+Business Media; 2013: in press.
 * Kopp RP, Kane CJ, Parsons JK. Chapter 11: Preparation for prostate biopsy. Prostate 	Cancer Diagnosis: PSA, Biopsy and Beyond, Ed. Jones, J Stephen. New York: Humana 	Press, 2013. 121-131.