User:HRShami/Peter Wilson (academic)

Peter Wilson is an American academic, researcher and author. He is a Professor of Medicine in the Cardiology Division and also Professor of Public Health at Emory University. He is Director of Epidemiology and Genomic Medicine at the Atlanta Veterans Affairs Medical Center. He served as the President of the American Society of Preventive Cardiology from 2008 to 2010.

Wilson is an active biomedical researcher with a focus on population science, cardiovascular disease, diabetes, lipids, and vascular disease risk prediction. He is the author or co-author of more than 600 peer reviewed journal articles and 4 books. He has been listed by the Science Citation Index as a highly cited author in Biomedicine from 1988 to 2003 and then again from 2003 to 2018. I have concentrated my research on the risk factors for coronary heart disease and diabetes mellitus, with an emphasis on biomarkers and biological mechanisms. This research has generally taken place in observational studies such as the Framingham Heart Study and other studies such as the Veterans Affairs electronic health records using a prospective study designs.

Wilson received the US Public Health Service Citation Award in 1989 and the US Public Health Service Commendation Medal in 1994. He was elected to the Association of American Physicians in 2005. He was given the 2017 Arthur Agatston Award by the Society of Computerized Clinical Tomography Award for Lifetime Achievement.

Education
Wilson was born and raised in New Haven, Connecticut. He received his B.S. from Yale College in 1970 and his MD from University of Texas Medical School at San Antonio in 1974. He completed his internal medicine training at Duke Medical Center and his endocrinology training at Duke and the National Heart, Lung, and Blood Institute in Bethesda.

Career
Wilson was a career National Heart, Lung, and Blood Institute investigator from 1978 to 1999 and retired as a Captain from the Public Health Service in 1999. From 1984 to 1999, he was a Clinical Associate Professor at Tufts University School of Medicine.

He was an Associate Professor of Medicine at Boston University School of Medicine from 1994 to 1999, becoming Full Professor in 2000. He was Director of the Laboratories at the Framingham Heart Study in Framingham from 1983 to 2003.

In 2003, Wilson left Boston University to join Medical University of South Carolina. At Medical University of South Carolina, he served as the Vice Chair of Medicine (Research) from 2005 to 2006. In 2006, he joined Emory University as an Professor in the Department of Medicine. At the same time, he was also appointed as Staff Physician and Director of Epidemiology and Genomic Medicine at Atlanta Veterans Affairs Medical Center. He later became a Professor of Public Health at Rollins School of Public Health at the institute.

Wilson is the former chair of the Lifestyle and Cardiometabolic Health Council (2012-2014) of the American Heart Association and has also held leadership positions in the AHA Epidemiology and Prevention Council. He served on the Food and Drug Administration Endocrine and Metabolic Disease Advisory Committee, on the American Board of Clinical Lipidology Examining Board, and the American Society of Preventive Cardiology. He served as the President of the American Society of Preventive Cardiology from 2008 to 2010. He served on the US Cholesterol Guidelines Committees in 2013 and was chair of the U.S. Cholesterol Evidence Writing Group in 2018. He served on the American Diabetes Association Practice Guideline Committee in 1998.

Wilson has been the Associate Editor (Epidemiology) for Journal of Clinical Lipidology since 2006.

Temporary Adviser to the World Health Organization for Multinational Study of Vascular Disease in Diabetes, 1981

Research and work
He has been principal investigator of the VA Merit grants “CVD Risk in Veterans,” and “Genetics and Cardiovascular Disease in Veterans”, a Million Veteran Program Merit grant

His most frequently cited article, was published in Circulation in 1998.

Risk factor prediction equations and algorithms
Throughout his career, the development and promulgation of novel ways to assess cardiovascular risk has been Wilson's most significant research focus. He is the originator of multivariable prediction of first cardiovascular events, first published in 1987, later updated and published as a special article in the journal Circulation in 1991, and then modified for categorical risk factors in 1998. The latter article entitled "Prediction of coronary heart disease using risk factor categories" is one of his most cited articles with over 10000 citations as of 2020. This approach, commonly called the Framingham Risk Score, has provided the underpinning of US cardiovascular risk assessment in 2013 and 2018 and has served as a key method to estimate risk for initial cardiovascular disease events in Europe, Latin America, Asia.

Cardiovascular risk factor research
Wilson's research has also been focused on factors related to cardiovascular disease outcomes. He has focused largely on lipids, diabetes, novel laboratory biomarkers, and genetics. The early work on the associations of HDL-C led to the incorporation of that lipid measurement into prognostication of coronary disease risk formulations. The CRP data complements the findings of others that have shown that inflammatory biomarkers are highly associated with heart disease risk.

1) Wilson PW, Abbott RD, Castelli WP. High density lipoprotein cholesterol and mortality. The Framingham Heart Study. Arteriosclerosis. 1988 Nov-Dec; 8(6):737-41. PubMed PMID: 3196218.

2) Abbott RD, Wilson PW, Kannel WB, Castelli WP. High density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction. The Framingham Study. Arteriosclerosis. 1988 May-Jun;8(3):207-11. PubMed PMID: 3370018.

3) Wilson PW, Pencina M, Jacques P, Selhub J, D'Agostino R Sr, O'Donnell CJ. C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circ Cardiovasc Qual Outcomes. 2008 Nov;1(2):92-7. doi: 10.1161/CIRCOUTCOMES.108.831198. Epub 2008 Nov 9. PubMed PMID: 20031795; PubMed Central PMCID: PMC3033831.

4) Wilson PW, Myers RH, Larson MG, Ordovas JM, Wolf PA, Schaefer EJ. Apolipoprotein E alleles, dyslipidemia, and coronary heart disease. The Framingham Offspring Study. JAMA. 1994 Dec 7; 272(21):1666-71. PubMed PMID: 7966894.

Diabetes, obesity, and metabolic syndrome
In this area, Wilson's research has been focused on investigating the development of diabetes mellitus and the role of metabolic syndrome factors in the etiology of both heart disease and diabetes mellitus. Approaches here include investigating the co-aggregation of metabolic syndrome risk factors, the prediction of diabetes mellitus on the basis of metabolic syndrome factors, and the added potential of considering the role of diabetes related genes.

1) Meigs JB, D'Agostino RB Sr, Wilson PW, Cupples LA, Nathan DM, Singer DE. Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study. Diabetes. 1997 Oct; 46(10):1594-600. PubMed PMID: 9313755.

2) Wilson PW, Meigs JB, Sullivan L, Fox CS, Nathan DM, D'Agostino RB Sr. Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med. 2007 May 28; 167(10):1068-74. PubMed PMID: 17533210.

3) Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D'Agostino RB Sr, Cupples LA. Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med. 2008 Nov 20;359(21):2208-19. doi: 10.1056/NEJMoa0804742. Erratum in: N Engl J Med. 2009 Feb 5;360(6):648. PubMed PMID: 19020323; PubMed Central PMCID: PMC2746946.

Awards and honors
a) Pauerstein Merit Scholarship Award by Medical School faculty for third year of medical school (1973) b) Mosby Scholarship Book Award for top five ranking students during 4th year of medical school (1974) c) Alpha Omega Alpha honor medical society (1974) d) ISI Highly Cited author (2004) [Clinical Medicine] for 1983-2003 and 2003-2013—among 200 most highly cited scientists in medical sciences over past 20 years e) U.S. Public Health Service-- Citation Award (1989), Commendation Medal (1994) f) Who’s Who in America (2000) g) Elected to the Association of American Physicians (2005) h) Millipub Award for Articles with >1000 citations (Emory University) 2010, total 5 articles (2014), total 7 articles (2016) i) Society of Computerized Cardiovascular Tomography Arthur Agatston Award for Contributions to Preventive Cardiology (2017) j) R. Wayne Alexander Award for Excellence in Research from Emory Medical School Dept of Medicine (2019)

Books

 * Coronary Risk Factors and Their Assessment. Science Press, London, 1992

2)	Atlas of Atherosclerosis: Risk Factors and Treatment (Second Edition) editor PWF Wilson, Current Science 2000 (Philadelphia, PA) 2000, pp 180-193

3)	Thompson G, Dean J, Wilson PWF: Dyslipidaemia in Clinical Practice. Martin Dunitz, London 2002 4)	Thompson G, Morrell J, Wilson P: Dyslipidaemia in Clinical Practice (Second Edition) (Informa Healthcare 2006)

Selected articles
1) Anderson KM, Odell PM, Wilson PW, Kannel WB. Cardiovascular disease risk profiles. Am Heart J. 1991 Jan;121(1 Pt 2):293-8. PubMed PMID: 1985385

2) Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998 May 12;97(18):1837-47. PubMed PMID: 9603539.

3) Wilson PW, D'Agostino R Sr, Bhatt DL, Eagle K, Pencina MJ, Smith SC, Alberts MJ, Dallongeville J, Goto S, Hirsch AT, Liau CS, Ohman EM, Röther J, Reid C, Mas JL, Steg PG; REACH Registry. An international model to predict recurrent cardiovascular disease. Am J Med. 2012 Jul; 125(7):695-703.e1. doi: 10.1016/j.amjmed.2012.01.014. PubMed PMID: 22727237.

4) Goff DC Jr, Lloyd-Jones DM, Bennett G, Coady S, D'Agostino RB Sr, Gibbons R, Greenland P, Lackland DT, Levy D, O'Donnell CJ, Robinson JG, Schwartz JS, Shero ST, Smith SC Jr, Sorlie P, Stone NJ, Wilson PW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014 Jul 1;63(25 Pt B):2935-59. doi: 10.1016/j.jacc.2013.11.005. Epub 2013 Nov 12. Erratum in: J Am Coll Cardiol. 2014 Jul 1;63(25 Pt B):3026. PubMed PMID: 24239921.