User:Hspanaser/Harkishan Singh

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Biographical Note:

Professor Harkishan Singh, presently Emeritus Professor at the Panjab University (Chandigarh, India), is a well recognized pharmaceutical academic, medicinal chemistry researcher and a science historian. He has experience of over half a century to his credit. He has worked at the Banaras Hindu University, University of Saugar, and the Panjab University in India, and abroad at the University of Maryland, University of Mississippi and the University of London.

His scientific research has been in organic chemistry, medicinal chemistry and natural products. Nearly 50 master and doctoral theses have been completed under his supervision. There have been published 125 original scientific research papers. 14 patents have been obtained. His research group has been successful in designing a clinically useful drug candocuronium iodide (INN) (chandonium iodide, HS-310), which is a synthetic azasteroid. Dr Singh has lectured on his research at several of the institutions and conferences in India, United States of America, Canada, United Kingdom and China. He delivered invited lectures at the Harvard School of Medicine and at the International Symposium on Molecular Structure sponsored by the International Union of Crystallography at Beijing.

As a science historian Professor Singh has examined the history of pharmaceutical developments in India of the nineteenth and twentieth centuries. His history research studies have been on pharmacopoeias and formularies, pharmaceutical education, pharmacy practice, biographies of pharmaceutical luminaries, and pharmaceutical journalism. He has published over fifty articles.

In addition to his scientific and history research papers, Dr Singh has authored and/or coauthored twelve books and nearly two dozens of review articles, including several book chapters. He has written extensively on educational, scientific, historical and professional issues. All told his total publications come well to over 300. Selected publications are listed later.

Professor Singh has been on many academic, scientific, professional and governmental bodies. He was a member of the Committee on Education in Medicinal Chemistry of the International Union of Pure and Applied Chemistry, which prepared the Report on the International Education of Medicinal Chemists (IUPAC Technical Reports Number 13; 1974).

His affiliations with several scientific and professional organizations include emeritus membership of the American Chemical Society, life memberships of the Indian Pharmaceutical Association and Association of Pharmaceutical Teachers of India, and memberships of the American Institute of History of Pharmacy and British Society for History of Pharmacy.

Professor Harkishan Singh is recipient of several scientific and professional awards and recognitions. He has been a National Fellow of the University Grants Commission, New Delhi. He has been General President of the Indian Pharmaceutical Congress. He received Eminent Pharmacist Award of the Indian Pharmaceutical Association. Dr Singh's standing as historian has been recognized through his election to the Academie Internationale d'Histoire de la PharacieThe University of the Sciences in Philadelphia conferred upon Professor Harkishan Singh the degree of Doctor of Science (Honoris Causa) in recognition of his distinguished academic career and outstanding contributions to scientific research in organic and medicinal chemistry and the history of pharmacy.

Neuromuscular Blocker Candocuronium (Chandonium)


 * The research papers and reviews marked with asterisk under Medical Chemistry refer to synthetic azasteroidal neuromuscular blockers and related aspects. A new neuromuscular blocker, initially named as Chandonium Iodide, was designed and synthesized by the research group of Professor Harkishan Singh at the Panjab University, Chandigarh. The pharmacological testing was carried out at the University at Strathclyde. The toxicity studies at the Central Drug Research Institute, Lucknow, did not reveal any adverse effects. The clinical studies were also successfully completed through the CDRI. The proceedings of the symposium on the clinical testing on Chandonium Iodide were published in the Journal of Anesthesiology and Clinical Pharmacology, 10, 109-151 (1994). The drug was cleared by the Ministry of Health, Government of India, for manufacturing and clinical use. The World Health Organization gave to the drug the INN designation Candocuronium Iodide. The drug is a potent non-depolarizing neuromuscular blocker with short duration of action. The injections can be sterilized by autoclaving. The preparation can be stored at room temperature without any loss of activity.

PROFESSOR HARKISHAN SINGH

Professor Emeritus, Panjab University, Chandigarh, India.

Page Web site. www.profharkishansingh.com

Birth:25 November 1928, Lyallpur District, India

Education:
 * B.Pharm., Panjab University, Ranked First, 1950
 * M.Pharm., Banaras Hindu University, 1952
 * Ph.D., Banaras Hindu University, 1956
 * D.Sc. (Honoris Causa), University of the Sciences in Philadelphia, 2014

Positions Held:

Lecturer in Pharmaceutical Chemistry, Banaras Hindu University, 1953-56

Assistant Professor of Pharmaceutical Chemistry, University of Saugar, 1956-64

Postdoctoral Research Fellow in Pharmaceutical Chemistry,  University of Maryland, U.S.A., 1958-61 (on leave of absence from the University of Saugar)

Reader in Pharmaceutical Chemistry, Panjab University, 1964-72

Visiting Professor and Research Fellow in Pharmaceutical Chemistry, University of Mississippi, U.S.A.1967-68 (on leave of absence from the Panjab University)

Commonwealth Academic Staff Fellow, University of London, U.K., 1971-72 (on leave of absence from the Panjab University)

Professor, Pharmaceutical Sciences (Pharmaceutical Chemistry), Panjab University, 1972-88

Head, Department of Pharmaceutical Sciences, Panjab University, 1976-81

Dean, Alumni Relations, Panjab University, 1979-84

Dean, Faculty of Pharmaceutical Sciences, Panjab University,1981-85

Emeritus Fellow (University Grants Commission), Panjab University, 1989-92

Professor Emeritus, Panjab University, since 2003

Awards and Honors

1975 Annual Award of the Shri Amrut Mody Research Foundation

President, Indian Pharmaceutical Congress, Thirty-third Session (1981), Jaipur

1983 G. P. Srivastava Memorial Award, Association of Pharmaceutical Teachers of India, Nagpur

1984 Professor M. L. Khorana Lectureship, Indian Pharmaceutical Association, Bombay

National Fellow, University Grants Commission, 1985-87; the only pharmaceutical academic to get this honour

1987 Ranbaxy Research Award in Pharmaceutical Sciences, Ranbaxy Research Foundation, New Delhi

Elected Member, Academie Internationale d'Historie de la Pharmacie, 1995

1998 Schroff Memorial National Award, Indian Hospital Pharmacists' Association, New Delhi

1999 Eminent Pharmacist Award, Indian Pharmaceutical Association, Bombay

Lifetime Achievement Award, Uttar Pradesh Technical University, 2006

Lifetime Achievement Award, Chandigarh Science Congress, 2007

Shri Bhojraj Panjamool Lifetime Achievement Award, Association of Pharmaceutical Teachers of India, Bangalore, 2007

Lifetime Achievement Award, 59th Indian Pharmaceutical Congress, Banaras Hindu University, 2007

Shri Ramanbhai B. Patel Foundation Lifetime Achievement Award, Indian Pharmaceutical Association ,Mumbai, 2010

Invited Lecture Delivered at Workshop on “Science in India in the 20th Century,” Asiatic Society, Kolkata, 2011

Doctor of Science (Honoris Causa) conferred by the University of the Sciences in Philadelphia, Philadelphia, Pennsylvania, U.S.A., 2014

Lifetime Achievement Award, Punjab Academy of Sciences, Patiala, 2015

Medicinal Chemistry: Medicinal Chemistry and Allied Fields Research Papers:

N. K. Basu and Harkishan Singh, Investigation of Orthosiphon pallidus Royle I, J. Am. Pharm. Assoc., Sci. Ed., 45, 595 (1956)

N. K. Basu and Harkishan Singh, Investigation of Orthosiphon pallidus Royle II, J. Am. Pharm. Assoc., Sci. Ed., 45, 598 (1956)

N. J. Doorenbos and Harkishan Singh, 3,6-Diaza-A,B-Bishom -cholestane-4,7-dione, J .Pharm. Sci., 50, 628 (1961)

N. J. Doorenbos and Harkishan Singh, Preparation of Azasteroids from Cholestenone and Progesterone, J. Pharm. Sci., 51, 418 (1962)

Harkishan Singh and V. V. Parashar, 3,17a-Diaza-A,D-bishomoandrost-4a-ene-4,17-dione, Tetrahedron Letters, 983 (1966)

Harkishan Singh and B. Razdan, Resolution of (±)-Tropinone Oxime, Tetrahedron Letters, 3243 (1966)

Harkishan Singh, S. Padmanabhan, A. K. Bose and I. Kugajevsky, The Schmidt Reaction with 4-Cholestene-3,6-dione, Chem. Ind. (London), 118 (1967)

Harkishan Singh and S. Padmanabhan, 3,7a-Diaza-A,B-bishomocholest-4a-ene-4,7-dione, Tetrahedron Letters, 3689 (1967)

Harkishan Singh and V. V. Parashar, Synthesis of 3,17a-Diaza-A,D-bishomoandrost-4a-ene-4,17-dione, Indian J. Chem., 6, 552 (1968)

Harkishan Singh, V. V. Parashar and T. K. Kaw, Degradation of 3-Aza-A-homo-22ß-spirost-4a-en-4-one to 3-Aza-A-homoandrost-4a-ene-4,17-dione, Steroids, 12, 577 (1968)

Harkishan Singh and B. Razdan, Studies on Tropinone Oxime, Indian. J. Chem., 6, 568 (1968)

Harkishan Singh and S. Padmanabhan, Some 5-En-7-ones and 7a-Aza-B-homo-5-en-7-ones in Spirostan, Androstane and Pregnane Series, Indian J. Chem., 7, 1084 (1969)

Harkishan Singh and A. S. Chawla, Isolation of Erysodine, Erysotrine and Hypaphorine from Erythrina suberosa Roxb. Seeds, Experientia, 25, 785 (1969)

Harkishan Singh and A. S. Chawla, Investigation of Erythrina Spp.III: Chemical Constituents of Erythrina suberosa Roxb. Seeds, J. Pharm. Sci., 59, 1179 (1970)

Harkishan Singh and A. S. Chawla, Investigation of Erythrina Spp. IV: Study of the Chemical Constituents of Seeds of Erythrina variegata var. orientalis, Planta Medica, 19, 71 (1970)

Harkishan Singh and A. S. Chawla, Investigation of Erythrina Spp. V. Study of Erythrina suberosa Leaves, Planta Medica, 19, 378 (1971)

Harkishan Singh, R. B. Mathur, N. J. Doorenbos, A. K. Bose and S. D. Sharma, 6-Aza-B-homo-cholestane-3,7-dione and Some Derivatives, Tetrahedron, 27, 3993 (1971)

Harkishan Singh and S. Padmanabhan, 3,7a-Diaza-A,B-bishomo-4a-ene-4,7-dione Azasteroid System and Related Studies, Indian J. Chem., 10, 355 (1972)

Harkishan Singh, R. B. Mathur and P. P. Sharma, 3-Aza-A-homo-4a-eno[3,4-d]tetrazole Steroid Analogues, J. Chem. Soc. Perkin I, 990 (1972)

Harkishan Singh,. S. Padmamabhan, A. K. Bose and I. Kugajevsky, Products of the Schmidt Reaction with Cholest-4-ene-3,6-dione, J. Chem. Soc., Perkin I, 993 (1972)

Harkishan Singh, D. Paul and V. V. Parashar, 4,17a-Diaza-D-homosteroids, J. Chem. Soc. Perkin I, 1204 (1973)

Harkishan Singh, P. P. Sharma and R. B. Mathur, Some 4-Azaspirostan Analogues and Related Studies, Indian J. Chem., 11, 1254 (1973)


 * I. G. Marshall, D. Paul and Harkishan Singh, Some Actions of 4,17a-Dimethyl-4,17a-diaza-D-homo-androstane Dimethiodide (HS-342), A New Neuromuscular Blocking Drug, J. Pharm. Pharmacol., 25, 441 (1973)


 * I. G. Marshall, D. Paul and Harkishan Singh, The Neuromuscular and Other Blocking Actions of 4,17a-Dimethyl-4,17a-diaza-D-homo-5?-androstane Dimethiodide (HS-342) in the Anaesthetized Cat, European J. Pharmacol., 22, 129 (1973).

Harkishan Singh, R. K. Malhotra, and V. V. Parashar, Azido-nitrile Formation in Schmidt Reaction and its Thermal Cyclisation to a Tetrazole, Tetrahedron Letters, 2587 (1973)

Harkishan Singh and V. K. Kapoor, Investigation of Strychnos Spp. I. Study of the Seed Oil of Strychnos potatorum, Lloydia, 36, 357 (1973)


 * Harkishan Singh and D. Paul, Chandonium Iodide (17a-Methyl- -pyrrolidino-17a-aza-D-homo-androst-5-ene Dimethiodide) and Other Quatenary Ammonium Steroid Analogues, J. Chem. Soc. Perkin I, 1475 (1974)


 * A. Gandiha, I. G. Marshall, D. Paul and Harkishan Singh, Neuromuscular and Other Blocking Actions of a New Series of Mono and Bis Quaternary Azasteroids, J. Pharm. Pharmacol., 26, 871 (1974)

Harkishan Singh, R. K. Malhotra and N. K. Luhadiya, Tetrazoles from Progresterone and 7-Oxocholest-5-en--yl Acetate, J. Chem. Soc. Perkin I, 1480 (1974)


 * A. Gandiha, I. G. Marshall, D. Paul, I. W. Rodger, W. Scott and Harkishan Singh, Some Actions of Chandonium Iodide, a New Short-acting Muscle Relaxant, in Anaesthetized Cats and on Isolated Muscle Preparations, Clin. Exp. Pharmacol. Physiol., 2, 159 (1975)

Harkishan Singh, A. S. Chawla, A. K. Jindal, A. H. Connor and J. W. Rowe, Investigation of Erythrina Spp. VII. Chemical Constituents of Erythrina variegata var. orientalis Bark, Lloydia, 38, 97 (1975)

Harkishan Singh, V. K. Kapoor, J. D. Phillipson and N. G. Bisset, Diaboline from Strychnos potatorum, Phytochemistry, 14, 587 (1975)

Harkishan Singh, R. K. Malhotra and V. V. Parashar, Novel Cleavage of 17-Oxosteroid in Schmidt Reaction and Thermal Cyclization of the Resultant Azido nitrile to Tetrazole, Indian J. Chem., 13, 761 (1975)

Harkishan Singh, D. Paul, R. K. Malhotra and T. R. Bhardwaj, Thin-Layer Chromatography of Some Lactam, Tetrazole, Basic, and Quaternary Azasteroids, J. Chromatogr., 114, 270 (1975).

Harkishan Singh and R. K. Malhotra, Some Steroidal Tetrazoles, J. Chem. Soc. Perkin I, 1404 (1975)

Harkishan Singh, V. K. Kapoor and M. S. Manhas, Investigation of Strychnos Spp. III. Study of Triterpenes and Steroids of Strychnos potatorum Seeds, Planta Medica, 28, 392 (1975)

Harkishan Singh, K. K. Bhutani and L. R. Gupta, Further Studies on the Schmidt Reaction with Cholest-4-ene-3,6-dione, J. Chem. Soc. Perkin I, 1210 (1976)

M. A. Mazid, R. A. Palmer, Harkishan Singh and D. Paul, The Crystal Structure and Stereochemistry of 17a-Methyl--pyrrolidinyl-17a-aza-D-homo-5-androstene (HS-309), Acta Crystallographica, B33, 3641 (1977)

Harkishan Singh, D. Paul, T. R. Bhardwaj, K. K. Bhutani and Jaishi Ram, Thin-layer Chromatography of Some Steroid Ketones, Oximes and Lactams, J. Chromatogr., 137, 202 (1977)

Harkishan Singh, T. R. Bhardwaj and D. Paul, Schmidt Reaction with -Acetoxypregn-5-ene-7, 20-dione, J. Chem. Soc. Perkin I, 1987 (1977)

Harkishan Singh, K. K. Bhutani, R. K. Malhotra and D. Paul, 7a-Aza-B-homo-[7a,7-d] tetrazole Analogues of Progesterone and Testosterone, Experientia, 34, 557 (1978)


 * Harkishan Singh, T. R. Bhardwaj, N. K. Ahuja and D. Paul, 17a-Methyl--(N-pyrrolidinyl)-17a-aza-D-homo-androstane Bis(methiodide) (Dihydrochandonium Iodide) and Certain Other Analogues of Chandonium Iodide, J. Chem. Soc. Perkin I, 305 (1979)


 * P. Teerapong, I. G. Marshall, A. L. Harvey, Harkishan Singh, D. Paul, T. R. Bhardwaj and N. K. Ahuja, The Effects of Dihydrochandonium and Other Chandonium

Analogues on Neuromuscular and Autonomic Transmission, J. Pharm. Pharmacol., 31, 521 (1979)


 * Harkishan Singh, T. R. Bhardwaj and D. Paul, A Chandonium Iodide Analogue Possessing an Acetylcholine-like Moiety, J. Chem. Soc. Perkin I, 2451 (1979)

Harkishan Singh, K. K. Bhutani, R. K. Malhotra and D. Paul, 7a-Aza-B-homo-[7a,7-d] tetrazole Analogues of Progesterone and Testosterone, J. Chem. Soc. Perkin I, 3166 (1979)


 * R. A. Palmer, M. A. Kalam, Harkishan Singh and D. Paul, Structure and Function of Synthetic Bisquatenary Neuromuscular Blocking Agents, J. Cryst. Mol. Str., 10, 31 (1980)

Harkishan Singh, A. S. Chawla, V. K. Kapoor and J. Kumar, Investigation of Erythrina Spp. X. Chemical Constituents of Erythrina blakei Bark, Planta Medica, 41, 101 (1981)

J. Hussain, R. A. Palmer, Harkishan Singh, T. R. Bhardwaj and D. Paul, The Structure of Tetrazole Steroid Analogues I. The Structure of -(5-Methyltetrazol-1-yl)-7a-aza-B-homoandrost-5-eno[7a,7-d]tetrazol--yl Acetate (HS-665), Acta Cryst., B37, 205 (1981)


 * I. G. Marshall, A. L. Harvey, Harkishan Singh, T. R. Bhardwaj and D. Paul, The Neuromuscular and Autonomic Blocking Effects of Azasteroids Containing Choline or Acetylcholine Fragments, J. Pharm. Pharmacol., 33, 451 (1981)

V. Gombar, V. K. Kapoor and Harkishan Singh, De novo Calculations on Antilipemic Activity of 4-(4-Chlorobenzyl)phenoxyacetic acid Esters, Arzneim. Forsch., 32, 7 (1982)

Harkishan Singh and D. Paul, 17-Hydroxy--methyl-androstano[3,4-c]-1', 2', 5'-oxadiazoles, Chem. Ind. (London), 329 (1982)

Harkishan Singh, D. Paul, T. R. Bhardwaj, A. K. Chaudhary and R. K. Gupta, Thin-layer Chromatography of Some Azasteroids, J. Chromatogr., 240, 264 (1982)

J. Hussain, I. J. Tickle, R. A. Palmer, Harkishan Singh, T. R. Bhardwaj and D Paul, The Structure of 17a-Methyl--pyrrolidinyl-17a-aza-D-homo-androstane (HS-691), Acta Cryst., B38, 130 (1982)

J. Hussain, I. J. Tickle, R. A. Palmer, Harkishan Singh and K. K. Bhutani, The Structure of Tetrazole Steroid Analogues. II. The Structure of 3,6-Diaza-A, B-bishomocholest-4a-eno- [3,4-d] [6,7-d]bistetrazole (HS-650) Monohydrate, Acta Cryst., B38, 2845 (1982)

A. I. El-Shora, R. A. Palmer, Harkishan Singh, T. R. Bhardwaj and D. Paul, The Crystal and Molecular Structure of 17a-(2-hydroxyethyl)--pyrrolidino-17a-aza-D-homo-5-androstene dimethiodide (HS-626), J. Cryst. Spect. Res., 12, 255 (1982)

J. Hussain, I. J. Tickle, R. A. Palmer, Harkishan Singh and K. K. Bhutani, The Structure of 4,6-Diaza-A,B-bishomochloest-4a-eno[4,3-d][6,7-d]bistetrazole (HS-649), Acta Cryst., C39, 297 (1983)

V. Gombar, V. K. Kapoor and Harkishan Singh, Quantitative Structure Activity: Relationships: Antiinflammatory Activity of Salicylic Acid Derivatives, Arzneim. Forsch., 33, 1226 (1983)

A. I. El-Shora, R. A. Palmer, Harkishan Singh, T. R. Bhardwaj and D. Paul, Crystal and Molecular Structures of 17a-(2-hydroxyethyl) - and -pyrrolidino-17a-aza-D-homo-5-androstenes: HS-625 form 1, (-pyrrolidino) and HS-625 form 2 (mixed- and -pyrrolidino epimers), J. Cryst. Spect. Res., 14, 89 (1984)

A. I. El-Shora, R. A. Palmer, Harkishan Singh and D. Paul, The Role of X-ray Crystallography in Drug Design: Identification of the Two Isomers -Hydroxy--methyl-5 ( and )-androstano[3, 4-c]-1', 2', 5' -oxadiazole (HS-804 and HS-805), J. Cryst. Spect. Res., 14, 315 (1984)

D. Paul, M. R. Yadav, R. K. Sharma, V. R. Agarwal and Harkishan Singh, -Pregnano[3,4-c]-1', 2',5',-oxadiazoles, Indian J. Chem., 24B, 1 (1985)


 * A. K. Chaudhary, V. K. Gombar and Harkishan Singh, Molecular Orbital Calculations on Some Neuromuscular Blocking Azasteroids, Indian J. Chem., 24B, 2 (1985)


 * Harkishan Singh and A. K. Chaudhary, Pharmacokinetics and Disposition of Chandonium Iodide in Rat, Indian J. Exp. Biol., 23, 253 (1985)


 * Harkishan Singh and A. K. Chaudhary, Pharmacokinetics and Disposition of Chandonium Iodide in Monkey, Indian J. Exp. Biol., 23, 258 (1985)


 * Harkishan Singh and A. K. Chaudhary, Protein Binding Studies with Chandonium Iodide, Indian J. Exp. Biol., 23, 262 (1985)


 * Harkishan Singh and A. K. Chaudhary, Assay, Formulation and Stability of Chandonium Iodide, Indian J. Exp. Biol., 23, 265 (1985)


 * Harkishan Singh and A. K. Chaudhary, Spectro-fluorimetric Assay of Chandonium Iodide, Indian J. Pharm. Sci., 47, 113 (1985)

Harkishan Singh, M. R. Yadav, S. P. Garg, R. K. Sharma and D. Paul, Steroidal [3,4-c]-1', 2', 5'-oxadiazoles, Heterocycles, 23, 2931 (1985)

T. K. Chattopadhyay, R. A. Palmer, Harkishan Singh and D. Paul, Crystal and Molecular Structure of 17a-(2-acetoxyethyl)-17a-aza-D-homo-5-androsten--yl acetate methiodide (HS-465), a monoquaternary azasteroid incorporating an acetylcholine-like moiety, J. Cryst. Spect. Res., 16, 233 (1986)

T. K. Chattopadhayay, J. N. Lisgarten, R. A. Palmer, Harkishan Singh and R. K. Malhotra, Structure of Tetrazole Steroid Analogues IV : Structure of 7a-aza-B-homocholest-5-eno[7a,7-d]tetrazol--yl acetate (HS-503), J. Cryst. Spect. Res., 17, 51 (1987)


 * T. R. Bhardwaj, S. Kapoor, C. C. Shekhar, D. P. Jindal and Harkishan Singh, Potential Azasteroidal Neuromuscular Blockers, Indian J. Chem., 27B, 209, (1988)


 * Harkishan Singh, R. K. Gupta and T. R. Bhardwaj, Chandonium Related Azasteroidal Neuromuscular Blockers, Indian J. Chem., 27B, 508 (1988)

D. P Jindal, S. K. Saxena and Harkishan Singh, Some Potential Azasteroidal Neuromuscular Blocking Agents, Indian J. Chem., 31B, 264 (1992)


 * J. Abraham, D. P. Jindal, Harkishan Singh, G. K. Patnaik and R. C. Srimal, Some More of Neuromuscular Blocking Chandonium Relations, Indian J. Chem., 31B, 566 (1992)


 * M. Kumar, S. K. Bhatia, T. R. Bhardwaj, Harkishan Singh, G. K. Patnaik and B. N. Dhawan, 3-(2-Dialkylaminoethoxy)-17a-methyl-17a-aza-D-homo-1,3,5(10)-estratriene Dimethiodide, Eur. J. Med. Chem., 27, 967 (1992)


 * J. Abraham, D. P. Jindal, Harkishan Singh, G. K. Patnaik and R. C. Srimal, Certain New Azasteroidal Bisquaternary Neuromuscular Blockers, Eur. J. Med. Chem., 28, 231 (1993)

Pharmaceutical History : Research Papers Harkishan Singh, Pharmaceutical Society of India: The Oldest Indian Pharmaceutical Organization, Indian J. Hist. Sci., 35, 67-76 (2000)

Harkishan Singh, The Pharmacopoeial History of Colonial India, Pharm. Hist., 30, 26 - 29 (2000)

Harkishan Singh, The Overseas Drug Trade of Colonial India, Pharm. Hist., 31, 4-9 (2001)

Harkishan Singh, European Pharmacies in Colonial India, Pharm. Hist., 31, 58-67 (2001)

Harkishan Singh, Apothecaries and Hospital Assistants, Pharm. Hist., 32, 15-16 (2002)

Harkishan Singh, The Western Medical System in Colonial India, Pharm. Hist., 33, 7- 15 (2003)

Harkishan Singh, The National Institute of Pharmaceutical Education and Research (NIPER): Conception and Creation, Pharma Times, 36 (10), 26-28 (2004)

Harkishan Singh, Diamond Jubilee Lecture: Pharmaceutical Education - Lahore to Chandigarh through Amritsar, Pharmacos, 34, 13-26 (2005)

Harkishan Singh, Jyotish Chandra Ghosh (1870-1957) – The Forgotten and Unsung Pioneer of Pharmacy, Indian J. Hist. Science, 41, 207-222 (2006)

Harkishan Singh, Professor Gorakh Prasad Srivastava – Personality, Pedagogy and Devotion to his Guru Schroff, Pharma Review, 5, 80-84 (2006-2007)

Harkishan Singh, A Place of Pilgrimage for Pharmacists – The Department of Pharmaceutics, Banaras Hindu University, Pharma Review Special Feature, 59th I P C, December 2007

Harkishan Singh, Ram Nath Chopra, Indian J. Hist. Sci, 2008 (in Press) Harkishan Singh, Professor Gorakh Prasad Srivastava – Personality, Pedagogy and Devotion to his Guru Schroff, Pharma Review, 5, 80 (2006-2007)

Harkishan Singh, A Place of Pilgrimage for Pharmacists – The Department of Pharmaceutics, Banaras Hindu University, Pharma Review Special Feature, 59th I P C, December 2007

Harkishan Singh, Ram Nath Chopra (1882-1973) – A Visionary in Pharmaceutical Science, Indian J. Hist. Sci, 43, 231 (2008)

Harkishan Singh, Khem Singh Grewal (1894-1965) – A Prominent Medico-Pharmaceutical Professional, Indian J. Hist. Sci., 43, 631 (2008)

Harkishan Singh, Modern Pharmacy in India – A Historical Perspective, Japanese J. Hist. Pharm., 43, 140 (2008)

Harkishan Singh, Manohar Lal Khorana and His Journalistic Promotion of the Profession, Pharma Times, 41(7), 11 (2009)

Harkishan Singh, Ratilal Prabhudas Patel – The Profession Need Resurrect His Name and Image, Pharma Times, 41(10), 10 (2009)

Harkishan Singh, Homi Ruttonji Nanji and His Promoting Development of Drug Industry, Pharma Times, 41(12), 30 (2009)

Harkishan Singh, Bishnupada Mukerji (1903-79) - A Medico-Pharmaceutical Professional of Eminence, Indian J. Hist. Sci., 44, 569 (2009)

Harkishan Singh, Tribhovandas Kalyandas Gajjar (1863-1920) – Pioneer Industrial Chemist of India, Indian J. Hist. Sci., 45, 419 (2010)

Harkishan Singh, Khwaja Abdul Hamied (1898-1972) – Pioneer Scientist Industrialist, Indian J. Hist. Sci., 45, 533 (2010)

Harkishan Singh, Charles W. White and Walter White, Pharm. Hist. (London), 41, 13 (2011)

Harkishan Singh, Harry Cooper 1888-1935, Pharm. Hist. (London), 41, 15 (2011)

Harkishan Singh, Professor Sankatha Prasad, Pharma Review, 9, 116 (2011)

Harkishan Singh, Professor William Basil Whalley (1916-2002), Pharm. Hist. (London), 41, 41 (2011)

Harkishan Singh and V. K. Kapoor, Professor Kidar Nath Gaind, Pharmacos (Panjab University), 38, 1 (2011)

Harkishan Singh, Apostolos Raptakos, Pharma Times, 45(2), 21 (2013)

Harkishan Singh, Amrut Vithaldas Mody, Pharma Times, 45(7), 12 (2013)

Harkishan Singh, Hospital Pharmacy in India: A Historical Perspective, Indian J. Hosp. Pharm., 50(5), 103 (2013)

Harkishan Singh, Madras Medical Journal, Pharm. Hist.(London), 43(4), 81 (2013)

Harkishan Singh, Speech at USciences Founders’ Day on Conferment of Doctor of Science (Honoris Causa), 20 February 2014, Indian J. Hist. Sci., 49(1), 84 (2014)

Harkishan Singh, David Waldie (1813-89), Pharm. Hist. (London), 44(2), 45 (2014)

Harkishan Singh, Professor Mahadeva Lal Schroff – Journalism as his Forte, Indian Pharm., 12(3, September), 17 (2014)

Harkishan Singh, Medicinal Chemistry Research in India, Indian J. Hist. Sci., 49(4), 413 (20 Views and Reviews : Review

Harkishan Singh, History of Modern Pharmacy in India- Progress of Research, Indian J. Hosp. Pharm., 43, 129-133 (2006)

Books

Five research monographs have been published in the series History of Pharmacy in India and Related Aspects:

Volume 1: Pharmacopoeias and Formularies (1994) Harkishan Singh

The book provides a documented account of sesquicentury of the Indian pharmacopoeial and formulary history. Several unknown or forgotten compendia have been rediscovered and their existence brought to surface. The information gleaned from official publications, contemporary periodicals, and government archives has been coordinated and collated to prepare this treatise.

ISBN 81-85731-30-6. Pages xvi+160, size 12x20cm

Volume 2: Pharmaceutical Education (1998) Harkishan Singh

The Pharmaceutical Education portrays a composite picture of the evolution and contemporary scenario of the whole gamut of pharmaceutical instructions and related aspects. The treatise dilates upon the historical perspectives of different items and issues pertaining to pharmaceutical education. The writing on each topic is supported with appropriate documentary evidences.

ISBN 81-85731-09-8. Pages xvi+204, size 12x20cm.

Volume 3: Pharmaceutical Practice (2002) Harkishan Singh

Starting with the history of introduction of the western medical system in India, the developments having bearing on pharmacy practice have been carefully investigated and the findings put in a readable form in the Pharmacy Practice. The narrative presented projects the state of pharmacy practice during colonial period and its progress since decolonization. The writing is fully documented and appropriately illustrated.

ISBN 81-85731-31-4. Pages xiv+226, size 12x20cm.

Volume 4: Builders and Awareness Creators of Modern Pharmacy 1: Mahadeva Lal Schroff and the Making of Modern Pharmacy (2005) Harkishan Singh

This research monograph is essentially a professional biography of Professor M. L. Schroff, also covering his life in general and personality characteristics. No facet of pharmacy escaped his attention. It is amazing that how an orphaned boy through his courage and confidence struggled to shape his own career, and accepted a challenge of building pharmacy for which he had not been trained or groomed. He became an icon and a legend in his lifetime. In the historical perspective Schroff emerges as the maker of modern pharmacy in India.

ISBN 81-85731-39-X. Pages xiv+216, size 12x20cm

Volume 5: Builders and Awareness Creators of Modern Pharmacy 2 (2008) Harkishan Singh

During the colonial rule the newly introduced health care system developed reasonably well but regrettably its pharmaceutical component stood neglected. It needed a long drawn out struggle to improve its lot. In this tome, second volumes on the builders and awareness creators of modern pharmacy, the lives and contribution of a dozen of forebears are profiled.

ISBN 81-85731-44-6. Pages xiv+ 362, size 12x20cm

Views and Reviews (2008) Harkishan Singh

Publisher: Association of Pharmaceutical Teachers of India Al-Ameen College of Pharmacy Bangalore 560027, India E-mail: aptialerts@yahoo.com

The Views and Reviews is a compilation of 101 of general articles published by Professor Harkishan Singh during the last over half a century. The material presented largely pertains to pharmaceutical education and research, pharmacy practice, industry, trade, statutory controls on drugs and pharmacy, colonial medicine and pharmacy, pharmaceutical journals, and biographies of some pharmaceutical luminaries. The narration of the sagas of several struggles by the profession is also of interest. He has also written about his personal and social experiences.

Pages: 634

Books:

Harkishan Singh, Pharmaceutical Society of India: The Oldest Indian Pharmaceutical Organization, Indian J. Hist. Sci., 35, 67-76 (2000) Harkishan Singh, The Pharmacopoeial History of Colonial India, Pharm. Hist., 30, 26 - 29 (2000) Harkishan Singh, The Overseas Drug Trade of Colonial India, Pharm. Hist., 31, 4-9 (2001) Harkishan Singh, European Pharmacies in Colonial India, Pharm. Hist., 31, 58-67 (2001) Harkishan Singh, Apothecaries and Hospital Assistants, Pharm. Hist., 32, 15-16 (2002) Harkishan Singh, The Western Medical System in Colonial India, Pharm. Hist., 33, 7- 15 (2003) Harkishan Singh, The National Institute of Pharmaceutical Education and Research (NIPER): Conception and Creation, Pharma Times, 36 (10), 26-28 (2004) Harkishan Singh, Diamond Jubilee Lecture: Pharmaceutical Education - Lahore to Chandigarh through Amritsar, Pharmacos, 34, 13-26 (2005) Harkishan Singh, Jyotish Chandra Ghosh (1870-1957) – The Forgotten and Unsung Pioneer of Pharmacy, Indian J. Hist. Science, 41, 207-222 (2006) Harkishan Singh, Professor Gorakh Prasad Srivastava – Personality, Pedagogy and Devotion to his Guru Schroff, Pharma Review, 5, 80-84 (2006-2007) Harkishan Singh, A Place of Pilgrimage for Pharmacists – The Department of Pharmaceutics, Banaras Hindu University, Pharma Review Special Feature, 59th I P C, December 2007 Harkishan Singh, Ram Nath Chopra, Indian J. Hist. Sci, 2008 (in Press) Harkishan Singh, Khem Singh Grewal (1894-1965) – A Prominent Medico-Pharmaceutical Professional, Indian J. Hist. Sci., 43, 631-644 (2008) Harkishan Singh, Modern Pharmacy in India – A Historical Prospective, Japanese J. Hist. Pharm., 43, 140-150 (2008) Harkishan Singh, Manohar Lal Khorana and His Journalistic Promotion of the Profession, Pharma Times, 41(7), 11-15 (2009) Harkishan Singh, Ratilal Prabhudas Patel – The Profession Need Resurrect His Name and Image, Pharma Times, 41(10), 10-12 (2009) Harkishan Singh, Homi Ruttonji Nanji and His Promoting Development of Drug Industry, Pharma Times, 41(12), 30-18 (2009) Harkishan Singh, Bishnupada Mukerji (1903-79) - A Medico Pharmaceutical Professional of Eminence, Indian J. Hist. Sci., 44, 569-594 (2009) Harkishan Singh, Tribhovandas Kalyandas Gajjar (1863-1920) – Pioneer Industrial Chemist of India, Indian J. Hist. Sci., 45, 419-429 (2010) Harkishan Singh, Khwaja Abdul Hamied (1898-1972) – Pioneer Scientist Industrialist, Indian J. Hist. Sci., 45, 533-558 (2010) Harkishan Singh, Charles W. White and Walter White, Pharm. Hist. (London), 41, 13-15 (2011) Harkishan Singh, Harry Cooper 1888-1935, Pharm. Hist. (London), 41, 15-16 (2011) Harkishan Singh, Professor Sankatha Prasad, Pharma Review, 9, 116-118 (2011) Harkishan Singh, Professor William Basil Whalley (1916-2002), Pharm. Hist. (London), 41, 41-43 (2011) Harkishan Singh and V. K. Kapoor, Professor Kidar Nath Gaind, Pharmacos (Panjab University), 38, 1-6 (2011) Harkishan Singh, Apostolos Raptakos, Pharma Times, 45(2), 21-22 (2013)

Books: Medicinal Chemistry and Allied Fields Harkishan Singh and V. K. Kapoor, Organic Pharmaceutical Chemistry, Vallabh Prakashan, Delhi, 1982; revised in 1987, 1991, 1994, 2000 Harkishan Singh, Amrik Singh Chawla and V. K. Kapoor, Medicinal Chemistry Research in India, National Information Centre for Drugs and Pharmaceuticals, Central Drug Research Institute, Lucknow, 1985 Harkishan Singh and V. K. Kapoor, Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, Delhi, 1996; revised in 2005, 2012

Books - Pharmaceutical History Harkishan Singh, Pharmacopoeias and Formularies, Vallabh Prakashan, Delhi, pp xvi+159. (1994) Harkishan Singh, Pharmaceutical Education, Vallabh Prakashan, Delhi, pp xvi+204. (1998) Harkishan Singh, Pharmacy Practice, Vallabh Prakashan, Delhi, pp xiv+226. (2002) Harkishan Singh, Builders and Awareness Creators of Modern Pharmacy 1: Mahadeva Lal Schroff and the Making of Modern Pharmacy,Vallabh Prakashan, Delhi, pp xvi+216. (2005) Harkishan Singh, Builders and Awareness Creators of Modern Pharmacy 2, Vallabh Prakashan, Delhi, pp xiv+362. (2008) Harkishan Singh, Views and Reviews 1, Association of Pharmaceutical Teachers of India, Bangalore, pp xii+627. (2008) Harkishan Singh, Builders and Awareness Creators of Modern Pharmacy 3: Medico-Pharmaceutical Professionals, Vallabh Prakashan, Delhi, pp xiii+174. (2009) Harkishan Singh, Builders and Awareness Creators of Modern Pharmacy 4:Sir Ram Nath Chopra? Work, Vision and Legacy, Vallabh Prakashan, Delhi, pp xi+266. (2010) Harkishan Singh, Pharmaceutical History of India, Vallabh Prakashan, Delhi, pp xvi+322. (2011) Harkishan Singh, Poineers of Pharmaceutical Industry, Vallabh Prakashan, Delhi, pp xii+200. (2011) Harkishan Singh, Views and Reviews 2, Association of Pharmaceutical Teachers of India, Bangalore, pp xii+300. (2012)

Archives:

Prof Singh has a colection of rare research studies, books, magazine , manuals for Pharmaqceutical students faculty and historians as a best library of pharmaceutical library at one point, beating universities and many big institutes. Writes have called it as a national archive.