User:Htafer/SCARNA7



Small Cajal body specific RNA 7 (also known as SCARNA7 or U90) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the methylation of residue 70 of U1 spliceosomal RNA.

scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.

SCARNA7 has a length ranging from 285 nt in T. guttata to 425 nt in G. aculeatus, a large part of which consists of an exceptionally long and quite well-conserved, roughly symmetric region between C and D', and C' and D box, respectively. The unusual length is caused by a repetitive G/U insert. SCARNA7 is found throughout all vertebrates, always in the same host gene (KPN4)