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The association between multimorbidity and mortality
Multimorbidity has been associated with an increased mortality. A systematic review of 26 articles found a positive association between multimorbidity and mortality. Individuals with two or more morbidities were found to have a higher risk of death compared with individuals without multimorbidity despite of a high heterogeneity found in the included studies. The risk of death was found to be positively associated with individuals with greater number of chronic conditions and reversely associated with socioeconomic status using meta-regression. In some cases, some combinations of diseases are associated with higher mortality. For example, people with morbidities affecting the heart, lung, and renal systems were found to have strong effects on mortality in a review. For people with severe mental illness, the lifespan can expect to live 10-20 years less than the general population.