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Single-pass membrane protein with coiled-coil domains 1, also known as SMC01, is a gene in humans that encodes the single-pass membrane and coiled-coil domain-containing protein isoform 1 and isoform 2.[1]

Function
SMCO1 expression is upregulated during the proliferative stage of liver regeneration and may play a role in liver repair.[2] SMCO1 mRNA is also highly expressed in adult heart tissue.[1]