User:I. Ly, UCSF/sandbox

Part 1

The main issue displayed for this article is that it needs citations from reliable sources. After reviewing the article, it seems that the group contributed a large amount of content with proper citations. The more important sections are extensively written but balanced in terms of content found in the subsections. Also, the language used is neutral and not too technical. Group 1’s proposed edits include rearranging topic headings, evaluating the introductory paragraph, creating topic headers, and adding further information. The group addressed all the proposed edits by revising the intro paragraph, editing/creating new headings, specifying the different types and uses of breast prostheses, and ensuring proper citation of information retrieved from a variety of sources.

Part 2

In terms of overall formatting, the article has concise heading/subheading titles. In the paragraphs, however, the citations are not consistent. For some citations, there appears to be an extra space after the period, while others do not have the extra space. With guidance from the Wikipedia style article for medicine-related articles, the ‘Uses’ section could be restructured as ‘Surgeries and procedures’ and then each separate surgery could be listed below. The current content seems fine for describing the uses, but can also include risks or complications/technique/etc, if relevant. There was also a sentence in the article that used the word ‘patient’, which would be better if it was reworded so it is written for a ‘general audience’. Lastly, the history section should be moved to the end of the article where it tends to appear according to the style guide.

Name of Article: Contraceptive mandate


 * Rated C-class; low-importance
 * Currently part of several WikiProjects

What improvements may be needed?

There currently seems to be many issues with perspectives/bias, so perhaps more neutrality is needed in the discussion. Some citations are missing in the article. The article has a lot of information. I am unsure of what content needs to be changed, but will look more carefully at the article. Overall, it seems like a complete article.

How will the changes affected others editing the article and how to address any concerns others may have?

I believe open discussion with other editors is very important to ensure others agree. Depending on what changes are made, more clarifications can be made on the topic.

It triggers an inflammatory response to release various inflammatory signaling molecules that leads to increased prostaglandin and metalloprotease release. These substances promote uterine contractions and cervical ripening which causes premature birth.

Complications[edit]
For mother and fetus, chorioamnionitis may lead to further short and long-term issues when microbes move to different areas or trigger the inflammatory response.

Maternal complications[edit]

 * Higher risk for C-section
 * Postpartum hemorrhage
 * Endometritis
 * Bacteremia (often involving Group B streptococcus and Escherichia coli)
 * Pelvic Abscess

Mothers with chorioamnionitis who undergo a C-section may be more likely to develop pelvic abscesses, septic pelvic thrombophlebitis, and infections at the surgical site.

Fetal complications[edit]

 * Fetal death
 * Neonatal sepsis

Neonatal complications[edit]

 * Perinatal death
 * Early onset neonatal sepsis
 * Septic shock
 * Neonatal pneumonia

In the long-term, infants may be more likely to experience cerebral palsy or neurodevelopmental disabilities, which seems to be related to the activation of the fetal inflammatory response syndrome (FIRS) when the fetus is exposed to infected amniotic fluid or other foreign entities. This systemic response results in neutrophil and cytokine release that can impair the fetal brain and other vital organs. Compared to infants with clinical chorioamnionitis, it appears cerebral palsy may occur at a higher rate for those with histologic chorioamnionitis. However, more research needs to be done to examine this association. There is also concern about the impact of FIRS on infant immunity as this is a critical time for growth and development. For instance, it may be linked to chronic inflammatory disorders, such as asthma.

Complications
For mother and fetus, chorioamnionitis may lead to further short and long-term issues. Intrapartum chorioamnionitis may be associated with neonatal pneumonia, meningitis, sepsis, and death.

Maternal complications

 * Higher risk for C-section
 * Postpartum hemorrhage
 * Endometritis
 * Bacteremia
 * Pelvic Abscess

Fetal complications

 * Fetal death
 * Neonatal sepsis

Neonatal complications

 * Perinatal death
 * Early onset neonatal sepsis
 * Septic shock
 * Neonatal pneumonia

Supportive Measures
Acetaminophen is often used for treating fever and may be beneficial for fetal tachycardia. There is possibly also an increased likelihood for neonatal encephalopathy when mothers have intrapartum fever.

[Editing]

In the long-term, infants may be more likely to experience cerebral palsy, bronchopulmonary dysplasia, or neurodevelopmental disabilities, which seems to be related to the activation of the fetal inflammatory response syndrome (FIRS). This systemic response results in neutrophil and cytokine release that can impair the fetal brain and other vital organs. Compared to infants with clinical chorioamnionitis, it appears cerebral palsy may occur at a higher rate for those with histologic chorioamnionitis. However, more research needs to be done to examine this association. There is also concern about the impact of FIRS on infant immunity as this is a critical time for growth and development. For instance, it may be linked to chronic inflammatory disorders, such as asthma.

In addition to the possible associations, chorioamnionitis may act as a risk factor for premature birth and periventricular leukomalacia. May combine outcomes and complications.

Outcomes[edit]
Chorioamnionitis has been found to have possible associations with numerous neonatal conditions. Intrapartum chorioamnionitis may be associated with neonatal pneumonia, meningitis, sepsis, and death, as well as long-term infant complications like bronchopulmonary dysplasia and cerebral palsy. Further, histological chorioamnionitis with fetal involvement is speculated to increase the likelihood for necrotizing enterocolitis by three-fold. This may occur because the fetal gut barrier is compromised and becomes more susceptible to conditions like sepsis.

This may be due to the impaired ability of the fetal gut barrier in response to conditions like sepsis. In addition to the possible associations, chorioamnionitis may act as a risk factor for premature birth and periventricular leukomalacia.