User:Immcarle57/sandbox

 Article Evaluation 

An evaluation of the HLA-DO Wiki page.  Possible Sources 
 * The HLA-DO page is categorized as a stub page--this designation is merited given the one-sentence content, improper reference and citation, and the lack of varying resources
 * Identifiers for this protein are listed in a table to the left of the page, as well as related 'surface antigens' on a table below
 * 'Immunodominant epitope selection' needs to be explained or linked to its Wiki page (if there is one)
 * An online version of the only reference provided is available--the current reference needs to be updated to reflect that
 * The only reference provided looks promising (primary literature, published in 2016, cited by two other papers, written by a Johns Hopkins professor with 44 other publications), however, I am wary of the fact that it was published in the F1000 Research publishing platform instead of a peer-reviewed journal
 * Other than my contributions, there are no discussions under the 'Talk' page of HLA-DO
 * In order to understand this topic, I will need to get into the primary literature
 * 1) Chen, Xinjian, and Peter E. Jensen. "Biological Function of HLA-DO (H2-O)." Critical Reviews in Immunology 34.3 (2014).
 * 2) Guce, Abigail I., et al. "HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism." Nature Structural and Molecular Biology 20.1 (2013): 90.
 * 3) Jiang, Wei, et al. "pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity." Scientific reports 5 (2015): 17333.
 * 4) Mellins, Elizabeth D., and Lawrence J. Stern. "HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation." Current opinion in immunology 26 (2014): 115-122.
 * 5) Poluektov, Yuri O., AeRyon Kim, and Scheherazade Sadegh-Nasseri. "HLA-DO and its role in MHC class II antigen presentation." Frontiers in immunology 4 (2013): 260.
 * 6) Poluektov, Yuri O., et al. "HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation." PLoS One 8.8 (2013): e71228.
 * 7) Pezeshki, Abdul Mohammad, et al. "HLA-DO increases bacterial superantigen binding to human MHC molecules by inhibiting dissociation of class II-associated invariant chain peptides." Human immunology 74.10 (2013): 1280-1287.