User:It's gonna be awesome/thermal amplitude

Thermal amplitude is literally thermal range all refering to the temperature range where a cold autoantibody or cold-reacting alloantibody can stay reactive. Thermal amplitude test is the method of determination of the relation between an autoantibody's reactivity and its surrounding temperature.

In practice, determining the upper limit and the lower limit in temperature for a given autoanibody's reactivity doesn't need to actually test the given autoanibody's reactivity at every degree but rather under 4 C, 22 C, 30 C, and 37 C respectively.

If the cold antibody's thermal amplitude was found to be ranging over 30 C, the cold antibody might be considered clinically significant at absent from titer result. In fact, the higher the upper limit of the cold antibody's thermal amplitude closer to core body temperature at 37 C, the greater the chance the cold antibody to be regarded clinically significant since it can destroy red blood cells for all time of the tested person who is alive. . In contrast, the kind of cold antibody only reactive at temperatures below 30 C is generally considered harmless, since it can only destroy red blood cells when one's body temperature falls under 30 C that is nearly impossible to observe from a living person.