User:JFauteck/sandbox

Jan-Dirk Fauteck (born May 9, 1962) is a German doctor and chronobiologist. Fauteck graduated from the University of Milan, Italy as a medical doctor for human medicine.

He is the author of "The Chronodiet," "Melatonin: The Mother Hormone of Chronobiology," and "Chronobiology: Living By Your Inner Clock" among others. He is also the author of an additional 37 e-books and over 60 scientific papers concerning chronobiology and its role on human health.

Fauteck has over two decades of research in the fields of chronobiology, melatonin and internal clocks and biological rhythms within the human organism.

Early life and education
Jan-Dirk Fauteck was born in Lemgo, Nordrhein-Westfalen, Germany. Fauteck attended Gymnasium Leopoldinum 2 in Detmold, Germany, graduating in 1982.

Fauteck began studying medicine in 1982 and graduated summa cum laude from the Institute of Pharmacology, University of Milan, Italy in 1992 with a medical degree as a “doctor of medicine and surgery.” During his time at the University of Milan, Faueck worked as a research assistant to Professor F. Fraschini in the Institute of Pharmacology.

In 1993, Fauteck received German recognition of the Italian board certification as a medical doctor, and in 1997 gained qualification as a specialist in human anatomy, histology and embryology at the University of Münster. From 1993 to 1997, Fauteck received a postdoctoral fellowship at the Institute of Anatomy, University of Münster, Germany, and was overseen by professor W. Wittkowski.

Scientific career and associations
Upon finalizing his fellowship at the University of Münster, Fauteck followed two positions working in the field of pharmaceuticals, clinical research and medical affairs. In 2002 he became the CEO of FIS international GbR, a private German consulting agency for “pharmaceutical/galenic scouting” and clinical development.

In 2004, Fauteck became the head of R&D of SymBalance GmbH & Co. KG, a German-based society involved with the research of new products designed to battle chronic pain.

In 2005, Fauteck received a diploma of preventive and anti-aging medicine and became board certificated by the European Society of Anti-Aging Medicine (ESAAM).

In 2006, Fauteck became the CEO of A.M.C.-Lodi srl, an Italian consulting agency for preventive and anti-aging medicine and sales office for different companies.

In 2011, Fauteck was named CEO of the European Academy of Preventive and Anti-Aging Medicine (EA³M) in Kalletal, Germany.

In 2016, Fauteck became an associate private docent at Jacobs University Bremen in the field of basics of anatomy. Along with fellow researchers and doctors, Prof. Bojidar Stankov, Dr. Alexander Lerchl, Dr. Wolfgang Clementi and Russel J. Reiter, Ph.D., Fauteck founded Interchron, an international forum of chronobiology in 2016, and remained on the board as secretary.

Association with Scientific Studies
Throughout the course of his studies, Fauteck has held the position of project manager and core investigator and clinician for a variety of scientific studies, including in 10 international food supplement marketing studies.

Among the many studies he led were;

·     melatonin dose finding study phase I (Nov 97 – Nov 98)

·     TU injections proof of concept, medical device (Sep 98 – Jan 99)

·     TU patch, proof of concept, medical device (Dec. 98- Dec 99)

·     DHEA-HRT study, phase I (May 98 – Jan 99)

·     DHEA-HRT study, phase II (Nov 99 – Sep 00)

·     DHEA dose finding study, phase I (Sep 01 – Feb 02)

·     DHEA dose finding study, phase I (Nov 02 – Apr 03)

·     TU injection study, phase III, medical device and pharmaceutical

product study (Jun 98 – Feb 02)

·     TU patch dose finding stud, phase I, medical device and

pharmaceutical product study (Jan 03 – Aug 03)

·     psoriasis efficacy study, phase II, (Jul 03 – Sep 03)

·     Ethanol/Isopropanol kinetic study, phase I (Nov 03- Dec 03)

·     Anesthesin® efficacy study, phase III (Nov 03 – Mar 04)

·     5-ALA fluorescence study, phase I (Feb. 04 – May 04)

·     Anaesthesulf® efficacy study, phase III (Nov 03 – Apr 04)

·     Anaesthesulf® Epicutan study phase I (May 04 – Jun 04)

·     EKC Epicutan study, phase I (May 04 – Jun 04)

·     Arnica Epicutan study, phase I (Aug 04 – Sep 04)

·     Anaesthesulf® Challenge Test phase I (Jul 04 – Sep 04)

·     5-ALA pharmacokinetic study, phase I (Apr 05 – May 05)

·     Felbinac Challenge Test phase I (July 05 – Sep 05)

·     5-FU-AK study, phase II (Jan 06 – March 06)

·     IDEA-Study, phase II (Dec-05- Oct 06)

·     ABC study, medical device study (Feb. 06 – Mar 07)

·     TIPI study, phase II (Oct 05- Oct 07)

·     IVF study, phase III (Sep. 2006 – Dec 07)

·     TIPI study, phase III (Jan 06 – Dec 08)

Short List of Scientific Publications
·       Böckers TM, Bockmann J, Fauteck J-D, Kreutz MR, Bock R, Wittkowski W. Pars tuberalis-specific cells in the ovine pituitary do express the common alpha-chain of glycoprotein hormones: an in situ hybridization and immunocytochemical study. Europ J Endocrinol 131: 540 - 546, 1994.

·       Fauteck J-D, Lerchl A, Bergmann M, Wittkowski W, Stankov B. High-affinity melatonin binding sites in the molecular layer of the human cerebellar cortex. In: Advances in Pineal Research 8. Möller M, Pevet P (eds.). John Libbey & Co Ltd pp 457 - 463, 1994.

·       Fauteck J-D, Lerchl A, Bergmann M, Möller M, Fraschini F, Wittkowski W, Stankov B. The adult human cerebellum is a target of the neuroendocrine system involved in the circadian timing. Neurosci Lett 179: 60 - 64, 1994.

·       Böckers TM, Niklowitz P, Bockmann J, Fauteck J-D, Wittkowski W, Kreutz MR. Daily melatonin injections induce cytological changes in Pars tuberalis-specific cells as observed under short photoperiod. J Neuroendocrinology 7: 607 - 613, 1995.

·       Fauteck J-D, Bockmann J, Böckers TM, Wittkowski W, Köhling R, Lücke A, Straub H, Speckmann E-J, Tuxhorn I, Wolf P, Pannek H, Oppel F. Melatonin reduces low Mg2+ epileptiform activity in human temporal slices. Exp Brain Res 107: 321 - 325, 1995.

·       Wittkowski W, Bockmann J, Böckers TM, Fauteck J-D, Kreutz M. "Zeitgeber" of the endocrine system: Pineal melatonin and pars tuberalis of the hypophysis. Neurology, Psychiatry and Brain Research 3: 1 - 10, 1995.

·       Böckers TM, Bockmann J, Fauteck J-D, Wittkowski W, Sabel BA, Kreutz MR. Evidence for gene transcription of adenohypophyseal hormones in the ovine pars tuberalis. Neuroendocrinology 63: 16 - 27, 1996.

·       Fischer B, Mußhoff U, Fauteck J-D, Madeja M, Wittkowski W, Speckmann E-J. Expression and functional characterization of a melatonin-sensitive receptor in Xenopus oocytes. FEBS Lett 381: 98 - 102, 1996.

·       Straub H, Köhling R, Lücke A, Fauteck J-D, Speckmann E-J, Moskopp D, Wassmann H, Tuxhorn I, Wolf P, Pannek H, Oppel F. The effects of verapamil and flunarizine on epileptiform activity induced by bicuculline and low Mg2+ in neocortical tissue of epileptic and primary non-epileptic patiens. Brain Res. 733: 307-311, 1996

·       Fauteck J-D, Schmidt H, Lerchl A, Kurlemann G, Wittkowski W. Melatonin in epilepsy: basic results of replacement therapy and first clinical results. Advances in Pineal Research 9. Möller M, Pevet P (eds.). John Libbey & Co Ltd,1998.

·       Fauteck J-D, Schmidt H, Lerchl A, Kurlemann G, Wittkowski W. Melatonin in epilepsy: basic results of replacement therapy and first clinical results. Bio Signals Recept. 8: 105-110, 1999

·       Fauteck JD, Dittgen M, Farker K. Melatonin and aging: relevance for clinical approach? J Endocrinol Invest (Italy), 22(10 Suppl): 90-1, 1999

·       Peschke E, Fauteck J-D, Mußhoff U, Schmidt F, Beckamnn A and Peschke D. Evidence for Melatonin receptors within pancreatic islets of rats: functional, autoradiographic and molecular investigations. J Pineal Res (Denmark), 28(3): 156-64, 2000

·       Fauteck JD Melatonin: is there a rationale for the clinical use of this hormone in sleep therapy? Z Arztl Fortbild Qualitatssich (Germany), 95(1): 39-43, 2001

·       Blumenau C, Berger E, Fauteck JD, et al., Expression and functional characterization of the mt1 melatonin receptor from rat brain in Xenopus oocytes: evidence for coupling to the phosphoinositol pathway. J Pineal Res (Denmark), 30(3): 139-46, 2001

·       Musshoff U, Riewenherm D, Berger E, Fauteck JD, et al., Melatonin receptors in rat hippocampus: molecular and functional investigations. Hippocampus, 12(2): 165-73, 2002

·       Saad F; Hoesl CE; Oettel M; Fauteck JD; Rommler A. Dehydroepiandrosterone treatment in the aging male--what should the urologist know? Eur Urol, p724-33; 48(5), 2005,

·       Fauteck JD and Kusztrich, Leben mit der inneren Uhr; Wie die Chronobiologie unsere Gesundheit, Wirtschaft und Gesellschaft beeinflusst, ECON; ISBN: 3430126703, 2005

·       Fauteck JD, Ackermann G, Birkel M, et al.; Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses. Arch Dermatol Res (Germany), 300(2) p53-60, Feb 2008

·       Kirschner MH; Lang RA; Breuer B; Breuer M; Gronover CS; Zwingers T; Bottrich JG; Arndt A; Brauer U; Hintzpeter M; Burmeister MA; Fauteck JD, Transdermal resorption of an ethanol- and 2-propanol-containing skin disinfectant. Langenbecks Arch Surg Jan;394(1):151-7 2009

·       Kusztrich I and Fauteck JD, Multi-Vitamine chronobiologisch optimieren: Für den intelligenten Einsatz von Vitaminen, Spurenelementen, Mineralstoffen..e-book from Imre Kusztrich and Dr. med. Jan-Dirk Fauteck, IGK-Verlag (17. April 2013)

·       Fauteck, JD and Kusztrich I, Handbuch der Chronobiologie: Gesund im Timetable der inneren Uhren, e-book Imre Kusztrich and Dr. med. Jan-Dirk Fauteck, IGK-Verlag (27. Juni 2013)

·       Fauteck, JD and Kusztrich, I. Das Phytamin Prinzip: Besser länger leben mit Phytostoffen und Hormonen Brandstätter Verlag; (20.11.2014)

·       Römmler A, and Fauteck JD, Die Chronobiologie der Hormone, in Hormone, Thieme Verlag (August 2014)

·       Fauteck JD and Platzer T; Die Chronodiät: Essen satt und abnehmen mit der inneren Uhr; Brandstätter Verlag (15. February 2016)

·       Fauteck JD Melatonin: die Geheimnisse eines wunderbaren Hormons, Brandstätter Verlag (planned for April 2017)