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Gabriel Hortobagyi, MD

Dr. Gabriel Hortobagyi is a practicing medical oncologist, a clinical and translational investigator, a research and academic administrator, and an educator. Dr. Hortobagyi chairs the Department of Breast Medical Oncology and directs the Breast Cancer Research Program at the University of Texas MD Anderson Cancer Center, where he also serves as professor of medicine and holds the Nellie B. Connally Chair in Breast Cancer.

Education

Dr. Hortobagyi studied medicine at the Universidad Nacional de Colombia, Bogotá, Colombia (Médico cirujano) (M.D.). He has also received honorary doctorates (Laurea Honoris Causa) from the University of Modena (Italy), la Universidad Autonoma de Noevo Leon (Mexico) and la Universidad de Buenos Aires (Argentina).

Research interests

Dr. Hortobagyi's major area of professional interest is the biology and treatment of breast cancer and he has worked extensively in the development of new agents and strategies for this disease. Dr. Hortobagyi is a clinical and translational investigator. Early in his career he designed strategies of combined modality therapy of locally advanced and inflammatory breast cancer. These strategies have been widely adopted for locally advanced and operable primary breast cancer. Dr. Hortobagyi and his group were lead investigators during the clinical development of the taxanes, paclitaxel and docetaxel; subsequently they led the integration of paclitaxel in the neoadjuvant therapy of primary breast cancer. Dr. Hortobagyi designed and conducted the definitive clinical trials that established the clinical contribution of bisphosphonates to the management of bone metastases. More recently, Hortobagyi and Hung developed the first gene therapy approach for the management of HER-2-overexpressing breast cancers. For the past five years, Dr. Hortobagyi’s group has concentrated on the development of transcriptional profiles for classification, prognostication and prediction of response to therapy.

Awards

Dr. Hortobagyi has received worldwide honors. In 2001, President Jacques Chirac named him Chevalier of the Order of la Legion d'Honneur de France. In 2005 he was named 2005 World Leader in Oncology and received the Gold Medal of the Mexican Society of Oncology. In 2009 he was made an ASCO Statesman and received the Charles A. LeMaistre Outstanding Achievement Award in Cancer, as well as the John Mendelsohn Lifetime Scientific Achievement Award, both from the University of Texas MD Anderson Cancer Center in Houston.

Social activities

Dr. Hortobagyi is member of numerous professional organizations both internationally and within the US. Since 1993 he has served as a member of the board of directors for the International Association of Breast Cancer Research. He has served as a member of the Board of Directors and is a Past-President of the American Society of Clinical Oncology; and he chaired the Health Advisory Board of the Susan G. Komen Breast Cancer Foundation, and is member of the Advisory Board for the Breast Cancer Research Foundation. Dr. Hortobagyi is past President of the International Society for Senology (breast diseases) and presently serves as Chair of the Breast Committee for the Southwest Oncology Group.

Personal life

Dr. Hortobagyi is married and has three daughters.