User:Jabbahwocky/sandbox

Jabbah sandbox!

Testing for INaP article

The persistent sodium current (I NaP ) is a form of sub-threshold, biological electric current contributed by non-inactivating voltage-gated sodium channels found in several central neurons. I NaP has been implicated in neuronal excitability, epilepsy, and neuropathic pain.

Biophysics
Persistent sodium current generation is hypothesized to occur by the incomplete inactivation of the voltage-gated sodium channel, where the channel becomes constitutively active and conducts sodium, creating a "persistently active" inward sodium current.