User:JamesGustafson/sandbox

=KIAA1257=

KIAA1257 is a protein coding gene located on chromosome 3q21.3. It is 116,654 base pairs long and encodes a 1,1179 amino acid long protein product. The gene contains 8 exons that can be variably spliced to produce 5 different transcript variants. The function of this gene is not well understood by the scientific community but it is known to interact with a rho GTPase activating protein and a TEA domain transcription factor.

The protein product has a weight of  46740 Da and an isoelectric point of 8.09. The gene is expressed in many areas throughout the body including muscle, the immune system, the nervous system, the digestive system, and the reproductive system.

Homology
KIAA1257 has orthologs in birds, reptiles, and amphibians. A ClustalW analysis showed KIAA1257 contains many highly conserved lysine residues in mammalian orthologs

Interactions
KIAA1257 has been shown to interact with RhoGTPase activating factor 1 and TEA domain family member 4.