User:Jeansong/ncibi

The National Center for Integrative Biomedical Informatics (NCIBI) is one of seven National Centers for Biomedical Computing (NCBCs) funded by the National Institutes of Health’s (NIH) Roadmap for Medical Research. NCIBI is based at the University of Michigan and is part of the Center for Computational Medicine and Bioinformatics (CCMB). NCIBI’s mission is to create targeted knowledge environments for molecular biomedical research to help guide experiments and enable new insights from the analysis of complex diseases. NCIBI was established in October 2005, and is funded by NIH grant U54-DA021519.

The Center develops conceptual models, computational infrastructure, an integrated knowledge repository, and query and analysis tools that enable scientists to effectively access and integrate biological data. Driving Biological Projects (DBPs) provide a starting point from which tool development is informed, launched, and tested. Current DBPs include gene fusion in cancers, major organ-specific complications of diabetes, nutrition and obesity, and co-morbid disease associations of bipolar disorder. In addition to testing tools for function, a separate team is dedicated to testing usability and user interaction.

Once tools are developed and validated, the Center disseminates data and software throughout the University and the broader biomedical research community. Various mechanisms such as training videos, tutorials, and demonstrations and presentations at prominent scientific conferences are used to share NCIBI data and software nationally and internationally.

Available Tools

In addition to the tools listed below, the enriched data contained in many NCIBI databases  is available from the Databases tab on the Try Our Tools page.

Exploratory Analysis

Conceptual Literature Searching