User:Jenjen96/sandbox

The article is out-of-date with the sources cited published between 1981 and 2002. More recent sources can be added as well as more updated and detailed information. The area of research it is now being used in could also be mentioned. Information from these two articles could also be included https://doi.org/10.1016/j.bmc.2017.06.001 and https://doi.org/10.1095/biolreprod.113.110692. DNA topoisomerase in cancer research should also be included. Secondly, the article is oversimplified. The information should be easy for the public to understand but not too simplified. Secondly, sentence structure is also a bit confusing. Some sentences could be phrased differently to have a better flow.

Visual Aid such as videos and pictures demonstrating what DNA topoisomerase does on a molecular level can be included.

Wiki Edit for Topoisomerase page needs to be updated. The most recent source is from 2010. Support information with more current resources. The mention of Topoisomerase in cancer research from http://webdb.outside.plattsburgh.edu:2048/login?url=http://dx.doi.org/10.1007/978-1-4614-0323-4 could be used. As well as finding more recent information on each type of topoisomerase. Also adding more links to the article to direct readers to keywords used for more information.

DNA Topoisomerase is also found in the mitochondria of cells. The Mitochondria generates ATP as well as plays a role in programmed cell death and aging.(n-Zen Tsai) The mitochondrial DNA is a circular, double-stranded DNA that requires the activity of topoisomerase to be replicated. The types of topoisomerase found in the mitochondria are I, IIβ, IIIα.