User:Jg9611/sandbox

Blabber
Sex Men are at greater risk of heart disease than pre-menopausal women.[6][17] Once past menopause, it has been argued that a woman's risk is similar to a man's[17] although more recent data from the WHO and UN disputes this.[6] If a female has diabetes, she is more likely to develop heart disease than a male with diabetes.[18]

Among middle-aged people, coronary heart disease is 2 to 5 times more common in men than in women.[15] In a study done by the World Health Organization, sex contributes to approximately 40% of the variation in the sex ratios of coronary heart disease mortality.[19] Another study reports similar results that gender difference explains nearly half of the risk associated with cardiovascular diseases[15] One of the proposed explanations for the gender difference in cardiovascular disease is hormonal difference.[15] Among women, estrogen is the predominant sex hormone. Estrogen may have protective effects through glucose metabolism and hemostatic system, and it may have a direct effect on improving endothelial cell function.[15] The production of estrogen decreases after menopause, and may change the female lipid metabolism toward a more atherogenic form by decreasing the HDL cholesterol level and by increasing LDL and total cholesterol levels.[15] Women who have experienced early menopause, either naturally or because they have had a hysterectomy, are twice as likely to develop heart disease as women of the same age group who have not yet gone through menopause.[citation needed]

Among men and women, there are notable differences in body weight, height, body fat distribution, heart rate, stroke volume, and arterial compliance.[16] In the very elderly, age-related large artery pulsatility and stiffness is more pronounced in women.[16] This may be caused by the smaller body size and arterial dimensions independent of menopause.[16]