User:Jlivschitz12

Topic Outline:

Introduction: Reaction: Properties and Characteristics Regulation: Inhibition: Clinical Applications: (make sure to use review articles, not primary sources)
 * Expand on this section, not enough written
 * Include more about its structure: tetrameter, 4 metal binding sites, etc
 * Leave mostly as it is, not much more information here
 * Reverse Reaction
 * Gluconeogenesis:
 * Add in a bit more detail as well
 * Hormonal Control
 * Effect of Metaformin
 * Isozymes in Vertebrates
 * In Cats
 * In Pigs
 * In Rat
 * Liver: Two types found
 * Already pretty thorough, fix it up a little bit and add some more detail
 * In rat liver
 * Carbohydrate response element binding protein
 * Inhibit by Oxygen Reactive Species (ROS)
 * Inhibit by Phenylalanine and Phenylpyruvate
 * Feedforward and Feedback Inhibition in Liver
 * Metabolism and Cancer Research
 * In e. Coli
 * M2 Splice isoform
 * Redox Metabolism in Respiring Cells
 * Parasitic Disease
 * Deficiency
 * Review of the last decade
 * Mutations
 * Progress of Molecular Genetics

Assay:
 * Methicillin-resistant Staphylococcus aureus
 * Briefly Mention and Discuss

My topic:
 * 1) Pyruvate kinase          Extra information